2-(三甲基硅基)噻唑合成路线

ELAN PHARMACEUTICALS, INC.; GALEMMO, Robert, A., Jr.; ARTIS, Dean, Richard; YE, Xiaocong, Michael; AUBELE, Danielle, L.; TRUONG, Anh, P.; BOWERS, Simeon; HOM, Roy, K.; ZHU, Yong-Liang; NEITZ, R., Jeffrey; SEALY, Jennifer; ADLER, Marc; BEROZA, Paul; ANDERSON, John, P.
Patent: WO2011/79114 A1, 2011 ;
Location in patent: Page/Page column 125 ;
WO 2011/079114 A1

19158-51-14-甲苯磺酰氰+

79265-30-82-(三甲基硅基)噻唑

1452-16-02-氰基噻唑

参考文献

Nagasaki, Izuru; Suzuki, Yumiko; Iwamoto, Ken-Ichi; Higashino, Takeo; Miyashita, Akira
Heterocycles, 1997 , vol. 46, # 1 p. 443 - 450

79265-30-82-(三甲基硅基)噻唑+

4755-77-5草酰氯单乙酯

33656-63-22-氧代-2-(噻唑-2-基)乙酸乙酯

参考文献

LIGAND PHARMACEUTICALS INC.; COLE, Andrew; MCGUINNESS, Brian, F.; SHAO, Yuefei; DONG, Guizhen; HENDERSON, Ian
Patent: WO2010/8775 A1, 2010 ;
Location in patent: Page/Page column 29-30 ;
WO 2010/008775 A1

79265-30-82-(三甲基硅基)噻唑+

541-41-3氯甲酸乙酯

14527-42-5噻唑-2-甲酸乙酯

参考文献

ELI LILLY AND COMPANY
Patent: WO2008/36579 A1, 2008 ;
Location in patent: Page/Page column 26 ;
WO 2008/036579 A1

79265-30-82-(三甲基硅基)噻唑+

541-41-3氯甲酸乙酯

14527-42-5噻唑-2-甲酸乙酯+

87636-26-8

参考文献

Journal of Organic Chemistry, , vol. 53, # 8 p. 1748 - 1761

79265-30-82-(三甲基硅基)噻唑+