1: With lithium hydroxide hydrate; dihydrogen peroxide in tetrahydrofuran; water T=20°C; 12 h; Inert atmosphere; 2: With hydrogenchloride in water pH=3; Inert atmosphere;
Birman's catalyst; 4-methoxybenzoic anhydride; N-ethyl-N,N-diisopropylamine in dichloromethane T=20°C; 12 h; Resolution of racemate; optical yield given as percent ee;
参考文献
Shiina, Isamu; Nakata, Kenya
Patent: US2010/234610 A1, 2010 ;
Location in patent: Page/Page column 6-7 ;
1: With lithium hydroxide hydrate; dihydrogen peroxide in tetrahydrofuran; water T=20°C; 12 h; Inert atmosphere; 2: With hydrogenchloride in water pH=3; Inert atmosphere;
hydrogen; Rult;(S)-2,2'-bis(diphenylphosphino)-1,1'-binaphthylgt;(OCOCH3)2 in methanol T=15 - 30°C; P=85120.1 Torr; 24 h; Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 52, # 14 p. 3174 - 3176
