2-苯基-2-氰基丁酸乙酯合成路线 (共 19 条)
反应条件
sodium ethanolate in toluene T=85°C; 4 h; Yield given;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 10 p. 1323 - 1328
反应条件
1: bromobenzene; cyanoacetic acid ethyl ester With 1,1'-bis-(diphenylphosphino)ferrocene; potassium tert-butylate; palladium diacetate in 1,4-dioxane T=70°C; 2: ethyl iodide in 1,4-dioxane T=70°C; 4 h; Further stages.;
参考文献
Wang, Xiang; Guram, Anil; Bunel, Emilio; Cao, Guo-Qiang; Allen, Jennifer R.; Faul, Margaret M.
Journal of Organic Chemistry, 2008 , vol. 73, # 4 p. 1643 - 1645
反应条件
N-benzyl-N,N,N-triethylammonium chloride in N,N-dimethyl-formamide T=100 - 105°C; 2.5 h;
参考文献
Sukhanov, N. N.; Yanovskaya, L. A.; Chetverikov, V. P.
Journal of Organic Chemistry USSR (English Translation), 1986 , vol. 22, # 6 p. 1206 - 1207
Zhurnal Organicheskoi Khimii, 1986 , vol. 22, # 6 p. 1338 - 1339
反应条件
sodium hydride in various solvent(s) T=120°C; 18 h;
参考文献
Hammond, Gerald B.; Plevey, Raymond G.; Sampson, Paul; Tatlow, John Colin
Journal of Fluorine Chemistry, 1988 , vol. 40, p. 81 - 98
参考文献
Journal of the American Chemical Society, , vol. 57, p. 352
反应条件
1: trimethyl phosphite silver nitrate complex / acetonitrile / 0.5 h / Ambient temperature 2: 0.5 h / 50 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 46, # 22 p. 4498 - 4501
反应条件
1: 84.7 percent / C2H5ONa / toluene / 2 h / Heating 2: NaOC2H5 / toluene / 4 h / 85 °C View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 10 p. 1323 - 1328
参考文献
Journal of Organic Chemistry, , vol. 46, # 22 p. 4498 - 4501
反应条件
ammonia; sodium amide
参考文献
Kogyo Kagaku Zasshi, , vol. 62, p. 204,206
Chem.Abstr., , vol. 57, p. 8492
参考文献
Chemische Berichte, , vol. 103, p. 210 - 221