1,3-双(二苯基膦)丙烷合成路线 （共 42 条）
反应条件
1,1,3,3-tetramethyldisiloxane; titanium(IV) isopropylate in various solvent(s) T=100°C; 7 h;
参考文献
Berthod, Mikael; Favre-Reguillon, Alain; Mohamad, Jahjah; Mignani, Gerard; Docherty, Gordon; Lemaire, Marc
Synlett, 2007 , # 10 p. 1545 - 1548
反应条件
1: lithium; triphenylphosphine in tetrahydrofuran T=50°C; 2: 3-chloropropyl chloride in tetrahydrofuran T=0 - 80°C; 3: With oxygen in methanol; water
参考文献
Journal of Organometallic Chemistry, , vol. 696, # 10 p. 2238 - 2251
反应条件
1: lithium; triphenylphosphine in tetrahydrofuran T=50°C; Inert atmosphere; 2: 3-chloropropyl chloride in tetrahydrofuran T=0 - 80°C; Inert atmosphere;
参考文献
Shatunov; Korlyukov; Lebedev; Sheludyakov; Kozyrkin; Orlov, V.Yu.
Journal of Organometallic Chemistry, 2011 , vol. 696, # 10 p. 2238 - 2251
反应条件
cesium hydroxide; 4 Angstroem MS in N,N-dimethyl-formamide T=23°C; 45 h;
参考文献
Honaker, Matthew T.; Salvatore, Ralph Nicholas
Phosphorus, Sulfur and Silicon and the Related Elements, 2004 , vol. 179, # 2 p. 277 - 283
反应条件
1: chloro-diphenylphosphine With sodium in anhydrous butyl ether T=105°C; 2 h; 2: 1-bromo-3-chloro-propane in anhydrous butyl ether T=105°C; 2 h;
参考文献
BASF Aktiengesellschaft
Patent: WO2006/84878 A1, 2006 ;
Location in patent: Page/Page column 19-20 ;
反应条件
1: diphenylphosphine oxide With cupric triflate; 1,1,3,3-tetramethyldisiloxane in toluene T=100°C; 9 h; Inert atmosphere; 2: With cesium hydroxide monohydrate in N,N-dimethyl-formamide; toluene T=20°C; 1 h; Inert atmosphereMolecular sieve; 3: 1,3-dibromo-propane in N,N-dimethyl-formamide; toluene T=100°C; 24 h; Inert atmosphereMolecular sieve;
参考文献
Li, Yuehui; Das, Shoubhik; Zhou, Shaolin; Junge, Kathrin; Beller, Matthias
Journal of the American Chemical Society, 2012 , vol. 134, # 23 p. 9727 - 9732
反应条件
in toluene T=100°C; Inert atmosphere;
参考文献
Van Overschelde, Michel; Vervecken, Elias; Modha, Sachin G.; Cogen, Simon; Van der Eycken, Erik; Van der Eycken, Johan
Tetrahedron, 2009 , vol. 65, # 32 p. 6410 - 6415
反应条件
lithium in tetrahydrofuran T=0°C; 0.5 h;
参考文献
Journal of the Chemical Society - Dalton Transactions, , # 14 p. 2379 - 2382
反应条件
1: Li, potassium t-butoxide / tetrahydrofuran 2: 65 percent View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1787 - 1790
反应条件
Inert atmosphereReflux;
参考文献
Van Overschelde, Michel; Vervecken, Elias; Modha, Sachin G.; Cogen, Simon; Van der Eycken, Erik; Van der Eycken, Johan
Tetrahedron, 2009 , vol. 65, # 32 p. 6410 - 6415
