1-(4-甲氧苯基)丙烷-1-OL合成路线 （共 45 条）
反应条件
1: triethylaluminum With titanium(IV) isopropylate; (R)-2,2'-dihydroxy-1,1'-binaphthyl in tetrahydrofuran; toluene T=20°C; 0.5 h; 2: 4-methoxy-benzaldehyde in tetrahydrofuran; toluene T=0°C; 5 h;
参考文献
Fan, Xiaohui; Guo, Kun; Guan, Yong-Hong; Fu, Lin-An; Cui, Xiao-Meng; Lv, Hao; Zhu, Hong-Bo
Tetrahedron Letters, 2014 , vol. 55, # 5 p. 1068 - 1071
反应条件
N,N,N',N,-tetramethylethylenediamine; methyl-diethoxy-silane; ferrous acetate T=65°C; 24 h;
参考文献
Nishiyama, Hisao; Furuta, Akihiro
Chemical Communications, 2007 , # 7 p. 760 - 762
反应条件
bis(1,5-cyclooctadiene)nickel (0); tri-tert-butyl phosphine; 1-(Prop-2-enyl)-1,2,3,4,5-pentamethylcyclopenta-2,4-dien in hexane; toluene T=0°C;
参考文献
Hirano, Koji; Yorimitsu, Hideki; Oshima, Koichiro
Organic Letters, 2005 , vol. 7, # 21 p. 4689 - 4691
反应条件
(R,R)-(2,4,6-Me3C6H2-CH=N-CH(Ph))2; (R)-3,3'-diphenylBINOL in hexane; dichloromethane 1.) -78 deg C, 4 h, 2.) -20 deg, 1 h;
参考文献
Ding, Kuiling; Ishii, Akihiro; Mikami, Koichi
Angewandte Chemie - International Edition, 1999 , vol. 38, # 4 p. 497 - 501
反应条件
in diethyl ether T=0 - 20°C;
参考文献
Ahern, Theresa; Mueller-Bunz, Helge; Guiry, Patrick J.
Journal of Organic Chemistry, 2006 , vol. 71, # 20 p. 7596 - 7602
反应条件
naphthalene; lithium in tetrahydrofuran T=-78 - 0°C; 2 h;
参考文献
Alonso, Emma; Ramon, Diego J.; Yus, Miguel
Tetrahedron, 1996 , vol. 52, # 45 p. 14341 - 14348
反应条件
1: With dichlorobis(dicyclohexylphosphinomethylpyridine)–ruthenium (II); potassium tert-butylate T=165°C; 24 h; Inert atmosphere; 2: With sodium tetrahydroborate in methanol T=20°C; Inert atmosphere;
参考文献
Organic Letters, , vol. 15, # 7 p. 1436 - 1439
反应条件
1: ethyl bromide With magnesium in diethyl ether 2 h; 2: 4-methoxy-benzaldehyde in diethyl ether; toluene T=20°C; Grignard reaction;
参考文献
Sharma, Anuj; Joshi, Bhupendra P.; Sinha, Arun K.
Bulletin of the Chemical Society of Japan, 2004 , vol. 77, # 12 p. 2231 - 2235
反应条件
1: ethyl bromide With magnesium in diethyl ether 2: 4-methoxy-benzaldehyde in diethyl ether; toluene T=20°C; 14 h;
参考文献
Tetrahedron, , vol. 62, # 5 p. 847 - 851
反应条件
1: 1-bromo-4-methoxy-benzene; (nBu)3MgLi in tetrahydrofuran; hexane T=0°C; 0.5 h; 2: propionaldehyde in tetrahydrofuran; hexane T=-78°C; 0.5 h; Further stages.;
参考文献
Inoue; Kitagawa; Shinokubo; Oshima
Journal of Organic Chemistry, 2001 , vol. 66, # 12 p. 4333 - 4339
