对氟苯乙腈合成路线

18293-53-3三甲基硅烷氰+460-00-4对溴氟苯→459-22-3对氟苯乙腈

参考文献

Wu, Lingyun; Hartwig, John F.
Journal of the American Chemical Society, 2005 , vol. 127, # 45 p. 15824 - 15832

参考文献

Ren, Yunlai; Yan, Mengjie; Zhao, Shuang; Sun, Yanpei; Wang, Jianji; Yin, Weiping; Liu, Zhifei
Tetrahedron Letters, 2011 , vol. 52, # 39 p. 5107 - 5109

151-50-8氰化钾→459-22-3对氟苯乙腈

参考文献

JANSSEN PHARMACEUTICA NV
Patent: WO2008/152081 A2, 2008 ;
Location in patent: Page/Page column 12 ;

928664-98-64-异恶唑硼酸频哪醇酯+460-00-4对溴氟苯→459-22-3对氟苯乙腈

参考文献

Velcicky, Juraj; Soicke, Arne; Steiner, Roland; Schmalz, Hans-Guenther
Journal of the American Chemical Society, 2011 , vol. 133, # 18 p. 6948 - 6951

352-33-01-氯-4-氟苯+1071-36-9氰基乙酸钠→459-22-3对氟苯乙腈

参考文献

Shang, Rui; Ji, Dong-Sheng; Chu, Ling; Fu, Yao; Liu, Lei
Angewandte Chemie - International Edition, 2011 , vol. 50, # 19 p. 4470 - 4474

143-33-9氰化钠+352-11-44-氟氯苄→459-22-3对氟苯乙腈

参考文献

Glushkov; L'vov; Davydova; Kudinova; Polyakova; Sanzharova; Anisimova
Pharmaceutical Chemistry Journal, 1997 , vol. 31, # 3 p. 155 - 157

16647-04-4(E)-6-甲基-3,5-庚二烯-2-酮+80482-67-3→459-22-3对氟苯乙腈+90433-70-8

参考文献

Barbachyn, Michael R.; Johnson, Carl R.; Glick, Milton D.
Journal of Organic Chemistry, 1984 , vol. 49, p. 2746 - 2748

140-29-4氰化苄→501-00-83-氟苯乙腈+326-62-52-氟苯基乙腈+459-22-3对氟苯乙腈+10036-43-8间氟氰苄

参考文献

Laurent, Eliane; Marquet, Bernard; Tardivel, Robert
Journal of Fluorine Chemistry, 1990 , vol. 49, # 1 p. 115 - 126

459-56-3对氟苯甲醇→459-22-3对氟苯乙腈

参考文献

Ren, Yunlai; Yan, Mengjie; Zhao, Shuang; Sun, Yanpei; Wang, Jianji; Yin, Weiping; Liu, Zhifei
Tetrahedron Letters, 2011 , vol. 52, # 39 p. 5107 - 5109

352-11-44-氟氯苄→459-22-3对氟苯乙腈

参考文献

Schliemann; Buege; Reppel
Pharmazie, 1980 , vol. 35, # 2 p. 69 - 72