1: bromobenzene With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 2: pentan-2-one in tetrahydrofuran; hexane T=-78 - 20°C; Further stages.;

1: With [RhCl(η2:η2-cycloocta-1,5-diene)]2; potassium carbonate in toluene T=90 - 110°C; 2: With hydrogenchloride in water; toluene

in diethyl ether T=20°C; 0.5 h;

oxygen; diisobutylaluminium hydride; (+/-)-Salsolidine; zirconocene dichloride in benzene T=20°C; 24 h;

in diethyl ether T=20°C; 0.5 h;

in diethyl ether 1) r. t., 2) reflux;

N,N,N',N',N'',N''-hexamethylphosphoric triamide; Sm(OTf)2 1.) THF, cyclohexane, RT, 1 h, 2.) THF, cyclohexane, RT, 0.5 h; Yield given. Multistep reaction;

1: 1.) samarium(III) trifluoromethanesulfonate, s-butyllithium, hexamethylphosphoric triamide / 1.) THF, cyclohexane, room temperature, 1 h, 2.) THF, cyclohexane, room temperature, 1 h 2: 1.) samarium(III) trifluoromethanesulfonate, s-butyllithium, hexamethylphosphoric triamide / 1.) THF, cyclohexane, room temperature, 1 h, 2.) THF, cyclohexane, room temperature, 1 h View Scheme

diethyl ether man erhitzt das Reaktionsprodukt auf 100grad und behandelt die Masse mit Eiswasser;

magnesium 1.) Et2O, 2.) Et2O, reflux, 2 h; Yield given. Multistep reaction;