1: ethyl 3-phenyl-2-propenoate; carbon dioxide With magnesium in N,N-dimethyl-formamide T=-15°C; 2: With chloro-trimethyl-silane in N,N-dimethyl-formamide T=-15°C; 1 h; 3: ethyl iodide With sodium hydrogencarbonate in N,N-dimethyl-formamide T=50°C; 5 h;
1: 1.) NaH / 1.) THF, 50 deg C, 1.5 h; 2.) reflux, 2 h 2: 1.) KOH, 2.) 2 M HCl / ethanol / 4 h / Heating 3: H2SO4 / benzene / 72 h / Heating View Scheme
参考文献
Breukelman, Stephen P.; Meakins, G. Denis
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 1627 - 1636
1: 85 percent / piperidine / benzene / 4 h / Heating 2: 67 percent / aq. ethanol / 7 h / 60 °C 3: 1.) KOH, 2.) 2 M HCl / ethanol / 4 h / Heating 4: H2SO4 / benzene / 72 h / Heating View Scheme
参考文献
Breukelman, Stephen P.; Meakins, G. Denis
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 1627 - 1636
oxygen; benzoic acid; Manganese (II) acetate; copper dichloride; palladium dichloride in 1,4-dioxane T=100°C; P=24001.9 Torr; 3.5 h; var. compositions of catalyst; Product distributionMechanism;
参考文献
El'man, A. R.; Boldyreva, O. V.; Slivinskii, E. V.; Loktev, S. M.
Bull. Russ. Acad. Sci. Div. Chem. Sci. (Engl. Transl.), 1992 , vol. 41, # 3 p. 552 - 557,435 - 438
