2-(三甲基硅基)苯并噻唑合成路线 （共 24 条）
反应条件
(i) nBuLi, Et2O, (ii) /BRN= 1209232/; Multistep reaction;
参考文献
Journal of Heterocyclic Chemistry, , vol. 8, p. 257 - 259
反应条件
potassium tert-butylate in N,N-dimethyl-formamide T=-60°C; 2 h; further catalyst: KF;
参考文献
Chemische Berichte, , vol. 118, # 9 p. 3872 - 3899
反应条件
2 h; from -78 deg C to RT;
参考文献
Chikashita, Hidenori; Itoh, Kazuyoshi
Heterocycles, 1985 , vol. 23, # 2 p. 295 - 300
反应条件
in diethyl ether Ambient temperature-78 deg C to room temp.;
参考文献
Synthesis, , # 8 p. 633 - 635
反应条件
in dichloromethane 3 h;
参考文献
PHARMACIA and UPJOHN COMPANY
Patent: WO2004/106345 A2, 2004 ;
Location in patent: Page 50 ;
参考文献
Pinkerton,F.H.; Thames,S.F.
Journal of Heterocyclic Chemistry, 1971 , vol. 8, p. 257 - 259
反应条件
in dichloromethane T=0°C; 15 h;
参考文献
Jutzi, Peter; Gilge, Ullrich
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 1011 - 1014
反应条件
CsF or silica-supported tetrabutylammonium fluoride in tetrahydrofuran Ambient temperature;
参考文献
Tetrahedron Letters, , vol. 23, # 48 p. 5079 - 5082
反应条件
1: 91 percent Chromat. / KOtBu / dimethylformamide / 0.25 h / -60 °C 2: 35 percent Chromat. / KOtBu / dimethylformamide / 1 h / -60 °C View Scheme
参考文献
Chemische Berichte, , vol. 118, # 9 p. 3872 - 3899
反应条件
in N,N-dimethyl-formamide T=-60°C; 0.25 h; var. temp., catalyst, conc. of KOtBu; Product distributionMechanism;
参考文献
Chemische Berichte, , vol. 118, # 9 p. 3872 - 3899
