2-对氯苯基-3-甲基丁腈合成路线 （共 16 条）
反应条件
potassium hydroxide in anhydrous xylene; water
参考文献
Ihara Chemical Industry Co., Ltd.
Patent: US4307034 A1, 1981 ;
反应条件
sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride T=60 - 70°C; 4 h;
参考文献
Nohira, Hiroyuki; Terunuma, Daiyo; Kobe, Shinzi; Asakura, Ikuko; Miyashita, Akira; Ito, Tasuku
Agricultural and Biological Chemistry, 1986 , vol. 50, # 3 p. 675 - 680
反应条件
sodium hydroxide; tetrabutylammomium bromide in water
参考文献
Bayer Aktiengesellschaft
Patent: US4650910 A1, 1987 ;
反应条件
sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride in water; benzene
参考文献
Sumitomo Chemical Company, Limited
Patent: US4012428 A1, 1977 ;
参考文献
Sumitomo Chemical Company, Limited
Patent: US4144264 A1, 1979 ;
反应条件
1: 76 percent / N-bromosuccinimide / CCl4 2: 65 percent / ethanol; H2O 3: 50 percent / KOH, Tween-80 / xylene View Scheme
参考文献
Volkov, Yu. P.; Kalinevich, V. M.; Trusova, E. I.; Bilevich, K. A.; Kryshtal', G. V.; Yanovskaya, L. Ya.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1986 , vol. 35, # 6 p. 1239 - 1242
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1986 , # 6 p. 1365 - 1368
反应条件
1: 65 percent / ethanol; H2O 2: 50 percent / KOH, Tween-80 / xylene View Scheme
参考文献
Volkov, Yu. P.; Kalinevich, V. M.; Trusova, E. I.; Bilevich, K. A.; Kryshtal', G. V.; Yanovskaya, L. Ya.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1986 , vol. 35, # 6 p. 1239 - 1242
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1986 , # 6 p. 1365 - 1368
反应条件
1.1: copper (I) cyanide / tetrahydrofuran; hexane; diethyl ether / 0.17 h / -30 - -10 °C / |Inert atmosphere 1.2: 0.33 h / -30 °C / |Inert atmosphere 1.3: -30 °C / |Inert atmosphere 2.1: dicyclohexyl-carbodiimide; pyridine; triethylamine / tetrahydrofuran; hexane; diethyl ether; dichloromethane / 12 h / 20 °C / |Inert atmosphere View Scheme
参考文献
Sengupta, Ritobroto; Weinreb, Steven M.
Synthesis (Germany), 2012 , vol. 44, # 18 p. 2933 - 2937
反应条件
tetrabutylammomium bromide; potassium hydroxide in toluene T=60°C; 2 h; MechanismKinetics; ConcentrationTemperature;
参考文献
Yadav, Ganapati D.; Jadhav, Yogeeta B.
Organic Process Research and Development, 2003 , vol. 7, # 4 p. 588 - 598
反应条件
1: 70 percent / H2SO4 / acetic acid; H2O 2: 100 percent / SOCl2 / benzene 3: 94.7 percent / benzene; pyridine View Scheme
参考文献
Volkov, Yu. P.; Kalinevich, V. M.; Trusova, E. I.; Bilevich, K. A.; Kryshtal', G. V.; Yanovskaya, L. Ya.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1986 , vol. 35, # 6 p. 1239 - 1242
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1986 , # 6 p. 1365 - 1368
