(E)-3-环己基-2-丙烯酸乙酯合成路线 (共 42 条)
反应条件
n-butyllithium; diisobutylaluminium hydride in tetrahydrofuran; hexanes; toluene
T=-78°C; Horner-Wadsworth-Emmons olefination; Inert atmosphere; stereoselective reaction;
参考文献
Webb, Damien; Jamison, Timothy F.
Organic Letters, 2012 , vol. 14, # 10 p. 2465 - 2467
反应条件
ruthenium carbene in dichloromethane
3 h; Heating;
参考文献
Hughes, Gregory; Kimura, Masanari; Buchwald, Stephen L.
Journal of the American Chemical Society, 2003 , vol. 125, # 37 p. 11253 - 11258
反应条件
4-(N,N-dimethlyamino)pyridine in N,N-dimethyl-formamide
T=25°C; Knoevenagel reaction;
参考文献
STUDIENGESELLSCHAFT KOHLE MBH
Patent: WO2006/119745 A2, 2006 ;
Location in patent: Page/Page column 5; 8 ;
反应条件
chromium dichloride in tetrahydrofuran
T=65°C; 2 h;
参考文献
Concellon, Jose M.; Concellon, Carmen; Mejica, Carmen
Journal of Organic Chemistry, 2005 , vol. 70, # 15 p. 6111 - 6113
反应条件
2,4,5-trifluorophenylboronic acid in tert-butyl methyl ether
T=50°C; 14 h;
参考文献
Manzano, Ruben; Ozores, Lidia; List, Benjamin; Job, Andreas; Rodefeld, Lars
Beilstein Journal of Organic Chemistry, 2009 , vol. 5, art. no. 3
反应条件
tetra-n-butylammonium acetate in dichloromethane
T=0°C; 1 h;
参考文献
Michida, Makoto; Mukaiyama, Teruaki
Chemistry Letters, 2008 , vol. 37, # 7 p. 704 - 705
反应条件
sodium hydride in tetrahydrofuran
-78 deg C to -25 deg C; Yield given. Yields of byproduct given;
参考文献
Ando, Kaori
Tetrahedron Letters, 1995 , vol. 36, # 23 p. 4105 - 4108
反应条件
manganese(IV) oxide in chloroform
Oxidation; Wittig reaction; 20 h; Heating;
参考文献
Blackburn, Leonie; Wei, Xudong; Taylor, Richard J. K.
Chemical Communications, 1999 , # 14 p. 1337 - 1338
反应条件
scandium tris(trifluoromethanesulfonate) in ethanol; dichloromethane
Meyer-Schuster rearrangement; 1 h;
参考文献
Engel, Douglas A.; Lopez, Susana S.; Dudley, Gregory B.
Tetrahedron, 2008 , vol. 64, # 29 p. 6988 - 6996
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene; sodium iodide in tetrahydrofuran
T=-78 - 0°C; Horner-Wadsworth-Emmons reaction;
参考文献
Ando, Kaori; Oishi, Tohru; Hirama, Masahiro; Ohno, Hiroaki; Ibuka, Toshiro
Journal of Organic Chemistry, 2000 , vol. 65, # 15 p. 4745 - 4749