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| CAS号 : | 1071-46-1 |
精确质量 : | 132.04200 |
| 分子式 : | C5H8O4 |
logP : | 0.02420 |
| 分子量 : | 132.11500 |
PSA : | 63.60000 |
丙二酸单乙酯 | |
Ethyl hydrogen malonate | |
1071-46-1 | |
C5H8O4 | |
132.11500 | |
63.60000 | |
0.02420 | |
132.04200 |
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n20/D 1.435(lit.)
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>230 °F
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106.5 °C3 mm Hg(lit.)
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1.119 g/mL at 25 °C(lit.)
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0.0155mmHg at 25°C
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3
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S26-S36
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Xi
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R36/37/38
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2918990090
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HS: 2918990090 Other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives |
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品名, 成分含量, 用途 |
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2918990090. 其他含其他附加含氧基羧酸（包括酸酐、酰卤化物、过氧化物和过氧酸及该税号的衍生物）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0% |
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2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
在装有搅拌器、滴液漏斗和温度计的三颈瓶中加入80g(0.470mol)丙二酸乙酯钾盐和50ml水。混合物冷却至5℃，于30min内加入40ml浓盐酸，其间温度应保持在10℃以下。抽滤，析出的氯化钾用75ml乙醚洗涤，水层用乙醚洗涤（3*50ml）。合并乙醚液，无水硫酸镁干燥，蒸出大部分溶剂后行减压蒸馏，余物在50℃/0.13kpa干燥1h,得到丙二酸单乙酯58~62g(93%~100%). | |
用作医药中间体。在二甲氨吡啶催化下，丙二酸单酯与a,b-不饱和醛反应，区域和立体选择性地制备2，4-不饱和酯。 |
