Ethoxyidazoxan合成路线 （共 4 条）
反应条件
1: N-bromosuccinimide, benzoyl peroxide / CCl4 / 7 h / Heating
2: 80 percent / HCl / diethyl ether / 14 h / 0 °C
3: 24 h / Ambient temperature
View Scheme
参考文献
Stillings, Michael R.; Chapleo, Christopher B.; Butler, Richard C. M.; Davis, J. Alfred; England, C. David; et al.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 8 p. 1054 - 1062
反应条件
hydrogenchloride
a) 0-10 deg C, 0.5 h, b) RT, overnight;
参考文献
Stillings, Michael R.; Chapleo, Christopher B.; Butler, Richard C. M.; Davis, J. Alfred; England, C. David; et al.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 8 p. 1054 - 1062
反应条件
triethylamine
1.) ether, a) 0-5 deg C, 16 h, b) RT, 8 h, 2.) ethanol, a) 0-5 deg C, 0.5 h, b) RT, overnight; Multistep reaction. Title compound not separated from byproducts;
参考文献
Stillings, Michael R.; Chapleo, Christopher B.; Butler, Richard C. M.; Davis, J. Alfred; England, C. David; et al.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 8 p. 1054 - 1062
反应条件
24 h; Ambient temperature;
参考文献
Stillings, Michael R.; Chapleo, Christopher B.; Butler, Richard C. M.; Davis, J. Alfred; England, C. David; et al.
Journal of Medicinal Chemistry, 1985 , vol. 28, # 8 p. 1054 - 1062
