反应条件
1: benzo[b]thiophene With n-butyllithium in tetrahydrofuran; hexane
T=-78°C; 1 h; Inert atmosphere;
2: With zinc(II) chloride in tetrahydrofuran; hexane
T=-78 - 20°C; Inert atmosphere;
3: 3-bromo-benzo[b]-thiophene With XPhos G3; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in tetrahydrofuran; hexane
T=20°C; Negishi Coupling; 12 h; Inert atmosphere;
参考文献
Yang, Yang; Oldenhuis, Nathan J.; Buchwald, Stephen L.
Angewandte Chemie - International Edition, 2013 , vol. 52, # 2 p. 615 - 619
Angew. Chem., 2013 , vol. 125, # 2 p. 643 - 647,5
