反应条件
1: tetrahydrofuran / 2 h / 0 °C 2: dipyridinium dichromate / dichloromethane / 20 h / 20 °C / Molecular sieve 3: NH2NH2•xH2O / 20 h / 130 °C 4: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium acetate / N,N-dimethyl-formamide / 20 h / 80 °C / 3102.97 Torr View Scheme
参考文献
Freeman-Cook, Kevin D.; Amor, Paul; Bader, Scott; Buzon, Leanne M.; Coffey, Steven B.; Corbett, Jeffrey W.; Dirico, Kenneth J.; Doran, Shawn D.; Elliott, Richard L.; Esler, William; Guzman-Perez, Angel; Henegar, Kevin E.; Houser, Janet A.; Jones, Christopher S.; Limberakis, Chris; Loomis, Katherine; McPherson, Kirk; Murdande, Sharad; Nelson, Kendra L.; Phillion, Dennis; Pierce, Betsy S.; Song, Wei; Sugarman, Eliot; Tapley, Susan; Tu, Meihua; Zhao, Zhengrong
Journal of Medicinal Chemistry, 2012 , vol. 55, # 2 p. 935 - 942