Pseudoephedrine合成路线 （共 47 条）
反应条件
triethylamine in dichloromethane T=20°C; Inert atmosphere;
参考文献
Lentsch, Christoph; Fuerst, Rita; Rinner, Uwe
Synlett, 2013 , vol. 24, # 20 art. no. ST-2013-B0718-L, p. 2665 - 2670
反应条件
sodium methylate in tetrahydrofuran T=23°C; 1 h;
参考文献
Myers, Andrew G.; Yang, Bryant H.; Chen, Hou; McKinstry, Lydia; Kopecky, David J.; Gleason, James L.
Journal of the American Chemical Society, 1997 , vol. 119, # 28 p. 6496 - 6511
反应条件
1: (+/-)-B-allenyl-10-trimethylsilyl-9-borabicyclo[3.3.2]decane; acrolein in diethyl ether T=-78°C; 2: (-)-lt;R-(R*,S*)gt;-Ephedrin in acetonitrile 4 h; Heating;
参考文献
Lai, Chunqiu; Soderquist, John A.
Organic Letters, 2005 , vol. 7, # 5 p. 799 - 802
反应条件
dimethyl hydrogen phosphite in benzene 2 h; Heating;
参考文献
Fazylov, S. D.; Gazaliev, A. M.; Vlasova, L. M.; Zhurinov, M. Zh.
Russian Journal of General Chemistry, 1996 , vol. 66, # 4 p. 678 - 679
Zhurnal Obshchei Khimii, 1996 , vol. 66, # 4 p. 696
反应条件
chlorine O.N-benzylidene-pseudoephedrine;
参考文献
Schmidt
Archiv der Pharmazie (Weinheim, Germany), 1914 , vol. 252, p. 99
Chem. Zentralbl., 1913 , vol. 84, # II p. 1310
参考文献
Davies
Journal of the Chemical Society, 1932 , p. 1580
Full Text Show Details
Schmidt
Archiv der Pharmazie (Weinheim, Germany), 1914 , vol. 252, p. 99
Chem. Zentralbl., 1913 , vol. 84, # II p. 1310
参考文献
Davies
Journal of the Chemical Society, 1932 , p. 1580
Full Text Show Details
Schmidt
Archiv der Pharmazie (Weinheim, Germany), 1914 , vol. 252, p. 99
Chem. Zentralbl., 1913 , vol. 84, # II p. 1310
参考文献
Davies
Journal of the Chemical Society, 1932 , p. 1580
Full Text Show Details
Schmidt
Archiv der Pharmazie (Weinheim, Germany), 1914 , vol. 252, p. 99
Chem. Zentralbl., 1913 , vol. 84, # II p. 1310
反应条件
sodium hydrogencarbonate; triethylamine in tetrahydrofuran; ethyl acetate
反应条件
n-butyllithium; lithium chloride Yield given. Multistep reaction;
参考文献
Krebs, Andreas; Ludwig, Verena; Pfizer, Jose; Duerner, Gerd; Goebel, Michael W.
Chemistry - A European Journal, 2004 , vol. 10, # 2 p. 544 - 553
