(3-丁炔-1-基氧基)(2-甲基-2-丙基)二苯基硅烷合成路线 （共 11 条）
反应条件
n-butyllithium; dimethylaluminum chloride in toluene T=-35°C; 3 h; Inert atmosphere;
参考文献
Chemistry - A European Journal, , vol. 20, # 10 p. 2879 - 2887
反应条件
N,N,N',N',N'',N''-hexamethylphosphoric triamide; n-butyllithium in tetrahydrofuran; diethyl ether T=-70°C;
参考文献
Viala, Jacques; Sandri, Jacqueline
Tetrahedron Letters, 1992 , vol. 33, # 34 p. 4897 - 4900
反应条件
4-(N,N-dimethlyamino)pyridine; triethylamine in dichloromethane
T=20°C; 2 h;
参考文献
Aurrecoechea, Jose M.; Alonso, Eva; Solay, Monica
Tetrahedron, 1998 , vol. 54, # 15 p. 3833 - 3850
反应条件
tris(dibenzylideneacetone)dipalladium(0) chloroform complex; diethylzinc in tetrahydrofuran; hexane
T=-78 - 20°C; 2.25 h;
参考文献
Maezaki, Naoyoshi; Yagi, Suguru; Yoshigami, Ryoko; Maeda, Jun; Suzuki, Tomoko; Ohsawa, Shizuka; Tsukamoto, Kouji; Tanaka, Tetsuaki
Journal of Organic Chemistry, 2003 , vol. 68, # 14 p. 5550 - 5558
反应条件
4-(N,N-dimethlyamino)pyridine in dichloromethane
参考文献
University of Pittsburgh-Of the Commonwealth System of Higher Education
Patent: US2012/207687 A1, 2012 ;
反应条件
Yield given. Multistep reaction;
参考文献
Nicolaou; Petasis; Li; et al.
Journal of Organic Chemistry, 1983 , vol. 48, # 26 p. 5400 - 5403
反应条件
Yield given. Multistep reaction;
参考文献
Nicolaou; Petasis; Li; et al.
Journal of Organic Chemistry, 1983 , vol. 48, # 26 p. 5400 - 5403
反应条件
1: 1-but-3-ynyloxy-2,2-dimethyl-1,1-diphenyl-1-silapropane With n-butyllithium in tetrahydrofuran
T=-78 - 0°C; 1 h;
2: formaldehyd in tetrahydrofuran
T=20°C; 3 h;
参考文献
Chakraborty, Tushar K.; Purkait, Subhas; Das, Sanjib
Tetrahedron, 2003 , vol. 59, # 46 p. 9127 - 9135
反应条件
1: n-BuLi / hexane / -78 °C
2: DIBAL-H / CH2Cl2 / -78 °C
View Scheme
参考文献
Zacharie, Boulos; Gagnon, Lyne; Attardo, Giorgio; Connolly, Timothy P.; St-Denis, Yves; Penney, Christopher L.
Journal of Medicinal Chemistry, 1997 , vol. 40, # 18 p. 2883 - 2894
反应条件
1: 73 percent / n-BuLi / tetrahydrofuran / -30 deg C up to RT
2: 73 percent / REDAL / diethyl ether / 0 °C
View Scheme
参考文献
Hale; Bhatia; Peak; Manaviazar
Tetrahedron Letters, 1993 , vol. 34, # 33 p. 5343 - 5346
