(E)-3-氯丙-2-烯腈合成路线 （共 17 条）
反应条件
in methanol 8 h; Heating; Yield given;
参考文献
Ege, Guenter; Franz, Hermann
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 1267 - 1273
参考文献
Scotti,F.; Frazza,E.J.
Journal of Organic Chemistry, 1964 , vol. 29, p. 1800 - 1808
参考文献
Scotti,F.; Frazza,E.J.
Journal of Organic Chemistry, 1964 , vol. 29, p. 1800 - 1808
参考文献
Journal of Organic Chemistry, , vol. 29, p. 1800 - 1808
反应条件
sodium hydroxide; 2,6-di-tert-butyl-4-methyl-phenol; tetra(n-butyl)ammonium hydrogensulfate; sodium carbonate 1.) benzene, 70 deg C, 36 h, 2.) CH2Cl2, room temperature, 3 days; Yield given. Multistep reaction;
参考文献
Almqvist, Fredrik; Ekman, Niklas; Frejd, Torbjoern
Journal of Organic Chemistry, 1996 , vol. 61, # 11 p. 3794 - 3798
参考文献
Movsum-zade,E.M. et al.
Zhurnal Organicheskoi Khimii, 1976 , vol. 12, # 8 p. 1687 - 1689,1659 - 1662
参考文献
Movsum-Zade,E.M. et al.
Journal of Organic Chemistry USSR (English Translation), 1977 , vol. 13, p. 1694 - 1696
Zhurnal Organicheskoi Khimii, 1977 , vol. 13, # 9 p. 1828 - 1830
反应条件
potassium tert-butylate in tert-butyl alcohol 3 h; Heating;
参考文献
Ege, Guenter; Franz, Hermann
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 1265 - 1266
反应条件
in methanol 5 h; Heating;
参考文献
Ege, Guenter; Franz, Hermann
Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 1267 - 1273
反应条件
1: 2-(4-bromophenyl)-2-methylpropionic acid With phenyllithium in tetrahydrofuran; toluene T=-80°C; 0.0833333 h; Inert atmosphere; 2: With n-butyllithium in tetrahydrofuran; hexane; toluene 0.333333 h; Inert atmosphere; 3: trans-β-chloroacrylonitrile Further stages;
参考文献
Zificsak, Craig A.; Shen, Yi; Lisko, Joseph G.; Theroff, Jay P.; Lao, Xuegang; Bollt, Oana; Li, Xiufen; Dorsey, Bruce D.; Kuwada, Scott K.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 5 p. 1850 - 1853
