1,5-二甲基-1H-吡唑-4-羧酸乙酯合成路线 （共 17 条）
反应条件
sodium hydroxide in ethanol 1 h; Heating;
参考文献
Huppatz
Australian Journal of Chemistry, 1983 , vol. 36, # 1 p. 135 - 147
反应条件
1: 92 percent / NaOH / ethanol / 1 h / Heating 2: Heating View Scheme
参考文献
Huppatz
Australian Journal of Chemistry, 1983 , vol. 36, # 1 p. 135 - 147
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 1 h; Heating;
参考文献
Chaloner; Crew; O'Neill; Storr; Yelland
Tetrahedron, 1992 , vol. 48, # 37 p. 8101 - 8116
反应条件
2,2,2-trifluoroethanol
T=0 - 20°C; 0.166667 h; regioselective reaction;
参考文献
Alinezhad, Heshmatollah; Tajbakhsh, Mahmood; Zare, Mahboobeh
Journal of Fluorine Chemistry, 2011 , vol. 132, # 11 p. 995 - 1000
反应条件
in ethanol
T=20°C; 24 h;
参考文献
Nishiwaki, Nagatoshi; Matsushima, Kazuo; Chatani, Miki; Tamura, Mina; Ariga, Masahiro
Synlett, 2004 , # 4 p. 703 - 707
反应条件
2,2,2-trifluoroethanol
T=20°C; 0.166667 h; regioselective reaction;
参考文献
Alinezhad, Heshmatollah; Tajbakhsh, Mahmood; Zare, Mahboobeh
Journal of Fluorine Chemistry, 2011 , vol. 132, # 11 p. 995 - 1000
反应条件
1: 70 percent / NaOEt / ethanol / 4 h / 80 °C
2: 70 percent / ethanol / 80 °C
3: ethanol / 24 h / 80 °C
View Scheme
参考文献
Nishiwaki, Nagatoshi; Matsushima, Kazuo; Chatani, Miki; Tamura, Mina; Ariga, Masahiro
Synlett, 2004 , # 4 p. 703 - 707
反应条件
1: 83 percent / hydrazine hydrate / ethanol / -10 - 20 °C
2: sodium ethoxide / ethanol / 2 h / Heating
View Scheme
参考文献
Huppatz
Australian Journal of Chemistry, 1983 , vol. 36, # 1 p. 135 - 147
反应条件
in ethanol
T=80°C; 24 h; Title compound not separated from byproducts;
参考文献
Nishiwaki, Nagatoshi; Matsushima, Kazuo; Chatani, Miki; Tamura, Mina; Ariga, Masahiro
Synlett, 2004 , # 4 p. 703 - 707
反应条件
in ethanol
T=20°C; 24 h; Title compound not separated from byproducts;
参考文献
Nishiwaki, Nagatoshi; Matsushima, Kazuo; Chatani, Miki; Tamura, Mina; Ariga, Masahiro
Synlett, 2004 , # 4 p. 703 - 707
