7-氨基-4-羧甲基香豆素合成路线 （共 10 条）
反应条件
sulfuric acid in acetic acid T=120°C; 5 h;
参考文献
Chemical and pharmaceutical bulletin, , vol. 32, # 10 p. 3926 - 3933
反应条件
water; sodium hydroxide Reflux;
参考文献
Punescu, Emilia; Louise, Ludivine; Jean, Ludovic; Romieu, Anthony; Renard, Pierre-Yves
Dyes and Pigments, 2011 , vol. 91, # 3 p. 427 - 434
反应条件
sodium hydroxide in water 12 h; Heating;
参考文献
Besson, Thierry; Joseph, Benoit; Moreau, Pascale; Viaud, Marie-Claude; Coudert, Gerard; Guillaumet, Gerald
Heterocycles, 1992 , vol. 34, # 2 p. 273 - 291
反应条件
1: 63 percent / 70percent H2SO4 / 8 h / 20 °C 2: NaOH; H2O / 16 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 67, # 3 p. 910 - 915
反应条件
1: 99 percent / ethyl acetate / Heating 2: 63 percent / 70percent H2SO4 / 8 h / 20 °C 3: NaOH; H2O / 16 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 67, # 3 p. 910 - 915
反应条件
1: 41 percent / 75percent H2SO4 / 3 h / 25 °C 2: 51.8 percent / concd. H2SO4 / acetic acid / 5 h / 120 °C View Scheme
参考文献
Chemical and pharmaceutical bulletin, , vol. 32, # 10 p. 3926 - 3933
反应条件
1: 66 percent / H2SO4 / 0.5 h / 90 °C 2: 78 percent / NaOH / H2O / 12 h / Heating View Scheme
参考文献
Heterocycles, , vol. 34, # 2 p. 273 - 291
反应条件
1: sulfuric acid / 0 - 20 °C 2: water; sodium hydroxide / Reflux View Scheme
参考文献
Dyes and Pigments, , vol. 91, # 3 p. 427 - 434
反应条件
1: conc. H2SO4 / 0 - 20 °C 2: conc. H2SO4; glacial AcOH / 5 h / 100 - 120 °C View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 38, # 1 p. 153 - 158
反应条件
1: ACA With chloro-trimethyl-silane; N-ethyl-N,N-diisopropylamine in dichloromethane 3 h; Heating; 2: (9H-Fluoren-9-yl)-methyl chloroformate in dichloromethane T=20°C; 11 h; Further stages.;
参考文献
Maly, Dustin J.; Leonetti, Francesco; Backes, Bradley J.; Dauber, Deborah S.; Harris, Jennifer L.; Craik, Charles S.; Ellman, Jonathan A.
Journal of Organic Chemistry, 2002 , vol. 67, # 3 p. 910 - 915
