4-苯基-1-对甲苯磺酰基哌啶-4-羧酸合成路线 （共 7 条）
反应条件
sulfuric acid 3 h; Heating;
参考文献
Al-Rashood; Madani; Ginawi; Ashraf; El-Obeid
Arzneimittel-Forschung/Drug Research, 1990 , vol. 40, # 11 p. 1242 - 1245
反应条件
ethanol; sulfuric acid
参考文献
Thorp; Walton
Journal of the Chemical Society, 1948 , p. 559
反应条件
sulfuric acid; water
3 h; Heating;
参考文献
Al-Rashood; Madani; Ginawi; Ashraf; El-Obeid
Arzneimittel-Forschung/Drug Research, 1990 , vol. 40, # 11 p. 1242 - 1245
反应条件
1: 80 percent / NaNH2 / toluene / 1 h / Heating
2: 93 percent / water, H2SO4 / 3 h / Heating
View Scheme
参考文献
Al-Rashood; Madani; Ginawi; Ashraf; El-Obeid
Arzneimittel-Forschung/Drug Research, 1990 , vol. 40, # 11 p. 1242 - 1245
反应条件
1: 84 percent / thionyl chloride / 1 h / 110 °C
2: 80 percent / NaNH2 / toluene / 1 h / Heating
3: 93 percent / water, H2SO4 / 3 h / Heating
View Scheme
参考文献
Al-Rashood; Madani; Ginawi; Ashraf; El-Obeid
Arzneimittel-Forschung/Drug Research, 1990 , vol. 40, # 11 p. 1242 - 1245
反应条件
1: 80 percent / NaNH2 / toluene / 1 h / Heating
2: 93 percent / water, H2SO4 / 3 h / Heating
View Scheme
参考文献
Al-Rashood; Madani; Ginawi; Ashraf; El-Obeid
Arzneimittel-Forschung/Drug Research, 1990 , vol. 40, # 11 p. 1242 - 1245
反应条件
1: 86 percent / 2N Na2CO3 / 1 h / 95 °C
2: 84 percent / thionyl chloride / 1 h / 110 °C
3: 80 percent / NaNH2 / toluene / 1 h / Heating
4: 93 percent / water, H2SO4 / 3 h / Heating
View Scheme
参考文献
Al-Rashood; Madani; Ginawi; Ashraf; El-Obeid
Arzneimittel-Forschung/Drug Research, 1990 , vol. 40, # 11 p. 1242 - 1245
