1,1,1,2-四氟乙烷合成路线 （共 120 条）
反应条件
fluorine T=45 - 60°C; Fluorination; 2.5 h; Product distribution; Further Variations:Temperatures;
参考文献
Moldavskii, Dmitrii D.; Bispen, Tatjana A.; Kaurova, Galina I.; Furin, Georgii G.
Journal of Fluorine Chemistry, 1999 , vol. 94, # 2 p. 157 - 167
反应条件
1: With zinc(II) chloride; lithium diisopropyl amide in tetrahydrofuran 1 h; 2: With copper(ll) bromide T=40°C; 2 h; Further stages.;
参考文献
Ramachandran, P. Veeraraghavan; Reddy, G. Venkat
Journal of Fluorine Chemistry, 2008 , vol. 129, # 5 p. 443 - 446
反应条件
fluorine T=200 - 250°C; Product distribution; Further Variations:Reagents;
参考文献
Pashkevich; Mukhortov; Alekseev; Asovich
Russian Journal of Applied Chemistry, 2002 , vol. 75, # 8 p. 1269 - 1274
反应条件
chlorine 1 h; Gas phasePhotolysis; Product distribution / selectivity;
参考文献
E.I. DUPONT DE NEMOURS AND COMPANY
Patent: WO2006/69108 A1, 2006 ;
Location in patent: Page/Page column 10; 11 ;
反应条件
1: 1,1,1-trifluoro-2-fluoroethane With zinc(II) chloride; lithium diisopropyl amide in tetrahydrofuran T=15 - 20°C; 2: 1,4-Diiodobenzene With tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran T=20°C; 28 h;
参考文献
Raghavanpillai, Anilkumar; Burton, Donald J.
Journal of Organic Chemistry, 2004 , vol. 69, # 21 p. 7083 - 7091
反应条件
1: 1,1,1-trifluoro-2-fluoroethane With zinc(II) chloride; lithium diisopropyl amide in tetrahydrofuran T=15 - 20°C; 2: 4-bromo-1-iodobenzene With tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran T=20°C; 18 h; Title compound not separated from byproducts;
参考文献
Raghavanpillai, Anilkumar; Burton, Donald J.
Journal of Organic Chemistry, 2004 , vol. 69, # 21 p. 7083 - 7091
反应条件
in diethyl ether T=-78 - 20°C; Addition; Title compound not separated from byproducts;
参考文献
Burdon; Coe; Haslock; Powell
Journal of Fluorine Chemistry, 1999 , vol. 99, # 2 p. 127 - 131
反应条件
1: 1,1,1-trifluoro-2-fluoroethane With zinc(II) chloride; lithium diisopropyl amide in tetrahydrofuran
T=15 - 20°C;
2: monoiodonaphthalene With tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran
T=60°C; 2 h;
参考文献
Raghavanpillai, Anilkumar; Burton, Donald J.
Journal of Organic Chemistry, 2004 , vol. 69, # 21 p. 7083 - 7091
反应条件
chlorine
1 h; Gas phasePhotolysis; Product distribution / selectivity;
参考文献
E.I. DUPONT DE NEMOURS AND COMPANY
Patent: WO2006/69108 A1, 2006 ;
Location in patent: Page/Page column 10; 11 ;
反应条件
Cl2 in neat (no solvent, gas phase)
Kinetics; Irradiation (UV/VIS); flow reactor, Xe flash lamp, 324 K; 5.3 - 19.6 Torr fluorocarbon, 1.7 -3.5 Torr Cl2, 0.2 - 1.1 Torr O2, 0 - 9.4 Torr N2, 0.6 - 6.2 Torr NO; not isolated, reaction followed by mass spectroscopy;
参考文献
Bhatnagar, Ashish; Carr, Robert W.
Chemical Physics Letters, 1995 , vol. 238, # 1-3 p. 9 - 15
