3-(4-硝基苯基)丙烷合成路线 （共 21 条）
反应条件
1: With methyl-diethoxy-silane; Rh<(S,S)-Phebox-i-Pr>(OAc)2(aq) in toluene
T=60°C;
2: With potassium fluoride; tetrabutyl ammonium fluoride in tetrahydrofuran; methanol; toluene
Further stages.;
参考文献
Kanazawa, Yoshinori; Nishiyama, Hisao
Synlett, 2006 , # 19 p. 3343 - 3345
反应条件
1: With 1-hydroxy-anthraquinone; (1-hydroxy-9,10-anthraquinon-2-yl)-terminated polystyrene; potassium carbonate in tetrahydrofuran
T=40 - 50°C; 72 h; Heating;
2: in methanol; water
Irradiation;
3: With air in methanol; water
0.333333 h; Further stages.;
参考文献
Blankespoor, Ronald L.; DeVries, Tim; Hansen, Eric; Kallemeyn, Jeffrey M.; Klooster, Aaron M.; Mulder, Jason A.; Smart, Robert P.; Vander Griend, Douglas A.
Journal of Organic Chemistry, 2002 , vol. 67, # 8 p. 2677 - 2681
反应条件
tri-n-butyl-tin hydride; tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran
Ambient temperature;
参考文献
Keinan, Ehud; Gleize, Pierre A.
Tetrahedron Letters, 1982 , vol. 23, # 4 p. 477 - 480
反应条件
hydrogen; (bis(1,2-diphenylphosphino)ethane)(2,5-norbornadiene)rhodium(I) tetrafluoroborate in benzene
T=55°C; P=10343 Torr; 24 h; Yield given. Yields of byproduct given;
参考文献
Chan, Albert S. C.; Pai, Cheng-Chao; Yang, Teng-Kuei; Chen, Shih-Min
Journal of the Chemical Society, Chemical Communications, 1995 , # 19 p. 2031 - 2032
反应条件
sodium hydrogencarbonate; palladium diacetate in water
T=60°C; 0.166667 h;
参考文献
Barbero, Margherita; Cadamuro, Silvano; Dughera, Stefano
Synthesis, 2006 , # 20 p. 3443 - 3452
反应条件
pyridinium chlorochromate in dichloromethane
1.5 h; Heating;
参考文献
Blankespoor, Ronald L.; DeVries, Tim; Hansen, Eric; Kallemeyn, Jeffrey M.; Klooster, Aaron M.; Mulder, Jason A.; Smart, Robert P.; Vander Griend, Douglas A.
Journal of Organic Chemistry, 2002 , vol. 67, # 8 p. 2677 - 2681
反应条件
1.1: 38.9 percent / HNO3; H2SO4 / 0.5 h / 50 °C
2.1: 98 percent / NaI / acetone / 17 h / Heating
3.1: (1-hydroxy-9,10-anthraquinon-2-yl)-terminated polystyrene; K2CO3; 1-hydroxy-9,10-anthraquinone / tetrahydrofuran / 72 h / 40 - 50 °C / Heating
3.2: H2O; methanol / Irradiation
3.3: 67 percent / air / H2O; methanol / 0.33 h
View Scheme
参考文献
Blankespoor, Ronald L.; DeVries, Tim; Hansen, Eric; Kallemeyn, Jeffrey M.; Klooster, Aaron M.; Mulder, Jason A.; Smart, Robert P.; Vander Griend, Douglas A.
Journal of Organic Chemistry, 2002 , vol. 67, # 8 p. 2677 - 2681
反应条件
C51H41P2Ru(1+)*C32H12BF24(1-) in toluene
T=20°C; 4 h;
参考文献
Manzini, Simone; Poater, Albert; Nelson, David J.; Cavallo, Luigi; Nolan, Steven P.
Chemical Science, 2013 , vol. 5, # 1 p. 180 - 188
反应条件
1.1: piperidine / ethanol / 5 h / Reflux; Inert atmosphere
2.1: sodium tetrahydroborate; acetic acid / dichloromethane / 1 h / 20 °C / Inert atmosphere
2.2: 2 h / 20 °C / Inert atmosphere
View Scheme
参考文献
Liu, Kai; Rao, Wei; Parikh, Hardik; Li, Qianbin; Guo, Tai L.; Grant, Steven; Kellogg, Glen E.; Zhang, Shijun
European Journal of Medicinal Chemistry, 2012 , vol. 47, # 1 p. 125 - 137
反应条件
thionyl chloride
Eintragen von Aluminiumchlorid;
参考文献
Ingold; Piggott
Journal of the Chemical Society, 1923 , vol. 123, p. 1482,1508
