反应条件
1.1: iodine; 1-(chloromethyl)-4-fluoro-1,4-diazoniabicyclo-[2.2.2]octane bis(tetrafluoroborate) / acetonitrile 2.1: n-butyllithium / tetrahydrofuran / -100 °C 2.2: -78 - 20 °C 3.1: hydrogenchloride; water View Scheme
参考文献
Hall, Adrian; Brown, Susan H.; Budd, Christopher; Clayton, Nicholas M.; Giblin, Gerard M.P.; Goldsmith, Paul; Hayhow, Thomas G.; Hurst, David N.; Naylor, Alan; Anthony Rawlings; Scoccitti, Tiziana; Wilson, Alexander W.; Winchester, Wendy J.
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 2 p. 497 - 501