zinc in benzene 0.166667 h; Ambient temperature;

oxygen; anhydrous sulphate; zirconium oxide; palladium dichloride T=170°C; P=45003.6 Torr; 3 h; Further byproducts given. Title compound not separated from byproducts;

boron trifluoride diethyl etherate in dichloromethane T=0 - 20°C;

copper diacetate; air; palladium diacetate 2 h; Heating;

sodium hydride in benzene 1.5 h; Heating;

triethylamine in water; acetonitrile T=45°C; 1 h;

Aliquatreg; 336; sodium hydrogencarbonate in dichloromethane; water 5 h; Ambient temperature;

1: nicotinamide adenine dinucleotide; pyridoxal 5'-phosphate; [3H]-L-Alanine; ammonium chloride; L-alanine dehydrogenase; alcohol dehydrogenase from Bacillus stearothermophilus; ω-transaminase from Chromobacterium violaceum; sodium hydroxide / water / 24 h / 20 °C / pH 8.5 / |Enzymatic reaction 2: triethylamine / water; acetonitrile / 1 h / 45 °C View Scheme

Yield given. Multistep reaction;

(i) Br2, SbCl5, liq. SO2, (ii) /BRN= 1731298/, (iii) /BRN= 1718733/; Multistep reaction;