1-(4-溴苯基)-3-(二甲基氨基)-2-丙烯-1-酮合成路线 （共 10 条）
参考文献
Lin, Yang-i; Lang, Stanley, A.
Journal of Organic Chemistry, 1980 , vol. 45, # 24 p. 4857 - 4860
反应条件
methanol; sodium in 1,4-dioxane 3 h; Reflux;
参考文献
Saleh, Tamer S.; Al-Omar, Mohamed A.; Abdel-Aziz, Hatem A.
Letters in Organic Chemistry, 2010 , vol. 7, # 6 p. 483 - 486
反应条件
1: 1.) Phosphorus oxychloride, 2.) Sodium perchlorate monohydrate / 1.) anhydr. Dichloromethane, room temp., 20 min; 0 deg C, 10 min, 2.) Dichloromethane/water, 0 deg C, 20 min 2: 73 percent / Sodium sulfide nonahydrate / dimethylformamide; H2O / 2 h / Ambient temperature 3: 61 percent / Pyridine, Hydroxylamine-O-sulfonic acid / ethanol; methanol / 0.5 h / Ambient temperature View Scheme
参考文献
Lin, Yang-i; Lang, Stanley, A.
Journal of Organic Chemistry, 1980 , vol. 45, # 24 p. 4857 - 4860
反应条件
ammonium acetate; K5CoIIIW12O40 T=115°C; 0.583333 h;
参考文献
Kantevari, Srinivas; Chary, Mahankhali Venu; Vuppalapati, Srinivasu V.N.
Tetrahedron, 2007 , vol. 63, # 52 p. 13024 - 13031
反应条件
hydrazine hydrate in ethanol T=80°C; 1 h;
参考文献
MERCK and CO., INC.
Patent: WO2009/151991 A1, 2009 ;
Location in patent: Page/Page column 128 ;
WO 2009/151991 A1
反应条件
hydroxylamine-o-sulphonic acid in methanol 0.333333 h; Ambient temperature;
参考文献
Rosa, Fernanda A.; Machado, Pablo; Bonacorso, Helio G.; Zanatta, Nilo; Martins, Marcos A. P.
Journal of Heterocyclic Chemistry, 2008 , vol. 45, # 3 p. 879 - 885
反应条件
pyridine; hydroxylamine hydrochloride in ethanol T=78°C; 16 h;
参考文献
Journal of Heterocyclic Chemistry, , vol. 45, # 3 p. 879 - 885
反应条件
pyridine; hydroxylamine hydrochloride in ethanol T=78°C; 16 h;
参考文献
Journal of Heterocyclic Chemistry, , vol. 45, # 3 p. 879 - 885
反应条件
1: 1.) Phosphorus oxychloride, 2.) Sodium perchlorate monohydrate / 1.) anhydr. Dichloromethane, room temp., 20 min; 0 deg C, 10 min, 2.) Dichloromethane/water, 0 deg C, 20 min 2: 73 percent / Sodium sulfide nonahydrate / dimethylformamide; H2O / 2 h / Ambient temperature View Scheme
参考文献
Lin, Yang-i; Lang, Stanley, A.
Journal of Organic Chemistry, 1980 , vol. 45, # 24 p. 4857 - 4860
反应条件
in N,N-dimethyl-formamide
T=20 - 75°C; 5 h; Product distribution / selectivity;
参考文献
Graneto, Mathew J.; Maddux, Todd M.; Masferrer, Jaime L.
Patent: US2008/125474 A1, 2008 ;
Location in patent: Page/Page column 14; 16 ;
