4-氨基-5-咪唑甲酰胺盐酸盐合成路线 （共 11 条）
反应条件
hydrogenchloride; sodium nitrite in water
反应条件
potassium carbonate in water
参考文献
Baig, Ghouse Unissa; Stevens, Malcolm F. G.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1987 , p. 665 - 670
反应条件
triethylamine in dichloromethane
反应条件
trichlorophosphate 3.5 h; Heating / reflux;
参考文献
EP1420021 A1, ;
Page 24 ;
反应条件
methanesulfonic acid in ethanol T=155 - 165°C; P=15751.6 Torr; Microwave irradiation;
参考文献
Hajduch, Jan; Cramer, John C.; Kirk, Kenneth L.
Journal of Fluorine Chemistry, 2008 , vol. 129, # 9 p. 807 - 810
反应条件
potassium hydroxide 1) DMF, 5 h, ice bath, 2) 0-8 deg C, 0.5 h; Yield given. Multistep reaction;
参考文献
Alhede; Priess Clausen; Juhl-Christensen; McCluskey; Preikschat
Journal of Organic Chemistry, 1991 , vol. 56, # 6 p. 2139 - 2143
反应条件
potassium hydroxide
1) DMF, 4 h, ice bath, 2) ice bath, 2 h; Yield given. Multistep reaction;
参考文献
Alhede; Priess Clausen; Juhl-Christensen; McCluskey; Preikschat
Journal of Organic Chemistry, 1991 , vol. 56, # 6 p. 2139 - 2143
反应条件
sodium acetate; acetic acid
参考文献
Bergmann et al.
Journal of Biological Chemistry, 1952 , vol. 194, p. 531,532
反应条件
sodium hydroxide in water
T=0 - 10°C; 3 h;
参考文献
Mokrushin, V. S.; Pospelova, T. A.; Bakulev, V. A.; Golovina, E. F.; Nikolaeva, S. L.; Pushkareva, Z. V.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1984 , vol. 20, # 2 p. 204 - 209
Khimiya Geterotsiklicheskikh Soedinenii, 1984 , vol. 20, # 2 p. 247 - 252
参考文献
Shaw
Journal of Biological Chemistry, 1950 , vol. 185, p. 439,442
