2,6-dichloropyridine-N-oxide; methanesulfonic acid; C45H57AuF6NO9PS2 in chloroform T=20°C; 0.25 h;

[Cp*Ru{PhP(C6H4-o-S)2}RuCp*](OTf)2; isopropyl alcohol in 1,2-dichloro-ethane T=60°C; 2 h;

copper(I) bromide in diethyl ether T=0 - 20°C; 1 h;

bis(acetylacetonate)nickel(II); triphenylphosphine in tetrahydrofuran T=20°C; Inert atmosphere; regioselective reaction;

copper(I) bromide in tetrahydrofuran T=60°C; 48 h; Inert atmosphere;

1.1: triphenylphosphine / dichloromethane / 0.5 h / 0 °C 1.2: 3 h / 0 °C 2.1: tert.-butyl lithium / tetrahydrofuran / -78 - 20 °C View Scheme

1.1: (methoxymethyl)-triphenylphosphonium chloride; potassium tert-butylate / tetrahydrofuran / 12 h / 0 - 20 °C 1.2: 12 h / |Reflux 2.1: triphenylphosphine / dichloromethane / 0.5 h / 0 °C 2.2: 3 h / 0 °C 3.1: tert.-butyl lithium / tetrahydrofuran / -78 - 20 °C View Scheme

1.1: isopropylmagnesium chloride / tetrahydrofuran / 1 h / 0 - 20 °C 1.2: 0.5 h / 20 °C 1.3: 4.5 h / |Reflux 2.1: potassium carbonate / water; methanol / 2 h / 0 - 20 °C View Scheme