2-羟基-4-甲基苯甲醛合成路线 (共 38 条)
反应条件
1-nitroethane; sodium acetate; acetic acid RefluxInert atmosphere;
参考文献
Mulzer, Michael; Coates, Geoffrey W.
Organic Letters, 2011 , vol. 13, # 6 p. 1426 - 1428
参考文献
Chuit; Bolsing
Bulletin de la Societe Chimique de France, 1906 , vol. <3> 35, p. 88
反应条件
sodium tetrahydroborate in methanol; water
参考文献
Payne, Peter; Tyman, John H. P.; Mehet, Satinder K.; Ninagawa, Akira
Journal of Chemical Research, 2006 , # 6 p. 402 - 405
反应条件
1: potassium carbonate; butanone / Erwaermen des Reaktionsprodukts mit aethanol. Kalilauge
2: hydrogen chloride
View Scheme
参考文献
Pappalardo; Duro
Bollettino Scientifico della Facolta di Chimica Industriale di Bologna, 1952 , vol. 10, p. 168
反应条件
1: 92 percent / potassium carbonate; tetrabutylammonium hydrogen sulphate / 1,2-dichloro-ethane / 3 h / 55 - 60 °C
2: 79 percent / sodium hydroxide / ethanol / 20 °C
View Scheme
参考文献
Reddy, Y. Thirupathi; Reddy, P. Narsimha; Mannan, Abdul; Kumar, B. Sunil; Gururaj
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2005 , vol. 44, # 5 p. 1079 - 1083
反应条件
propionic acid sodium salt
参考文献
Nakabayashi; Yamasaki
Yakugaku Zasshi, 1954 , vol. 74, p. 590
Chem.Abstr., 1954 , p. 10721
反应条件
potassium carbonate in butanone
4 h; Heating;
参考文献
Chapleo, Christopher B.; Myers, Peter L.; Butler, Richard C. M.; Davis, John A.; Doxey, John C.; et al.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 5 p. 570 - 576
反应条件
potassium carbonate in N,N-dimethyl-formamide
1.5 h; RefluxMolecular sieve;
参考文献
Byun, Ji Hun; Kim, HyeYun; Kim, YoungSoo; Mook-Jung, Inhee; Kim, Dong Jin; Lee, Won Koo; Yoo, Kyung Ho
Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 20 p. 5591 - 5593