反应条件
1: ethylmagnesium bromide / diethyl ether / 3.5 h / Heating 2: diethyl ether / 4 h / 0 - 2 °C 3: 79 percent / pyridine / 1.) -5 deg C, 6 h; 2.) 0 deg C, 12 h 4: 53 percent / sodium iodide, zinc dust / tetrahydrofuran / 1.) 65-70 deg C, 3 h; 2.) 20 deg C, 3 h 5: 1.) 2percent O3 in O2; 2.) sodium tetrahydroborate / 1.) cyclohexane, methanol; 2.) room temp., 15 h 6: 1.) isobutylmagnesium bromide; 2.) C5H5TiCl2 / 1.) diethyl ether, 0 deg C, 15 min; 2.) room temp., 1-1,5 h View Scheme
参考文献
Sorochinskaya, A.M.; Kovalev, B.G.
Journal of Organic Chemistry USSR (English Translation), 1991 , vol. 27, # 4.1 p. 621 - 624
Zhurnal Organicheskoi Khimii, 1991 , vol. 27, # 4 p. 722 - 727
