1-(3,4-亚甲二氧基苯基)-1-丙醇合成路线 （共 12 条）
反应条件
chloro-trimethyl-silane; acetonitrile; sodium iodide in hexane 24 h; Ambient temperature;
参考文献
Sakai, Takashi; Miyata, Kazuyoshi; Utaka, Masanori; Takeda, Akira
Tetrahedron Letters, 1987 , vol. 28, # 33 p. 3817 - 3818
反应条件
pyridinium chlorochromate in dichloromethane T=20°C; 16 h;
参考文献
Joncour, Agnes; Decor, Anne; Liu, Jian-Miao; Tran Huu Dau, Marie-Elise; Baudoin, Olivier
Chemistry - A European Journal, 2007 , vol. 13, # 19 p. 5450 - 5465
参考文献
Mameli
Atti della Accademia Nazionale dei Lincei, Classe di Scienze Fisiche, Matematiche e Naturali, Rendiconti, 1904 , vol. <5> 13 II, p. 320
Gazzetta Chimica Italiana, 1904 , vol. 34 II, p. 416
反应条件
1: in diethyl ether
T=20°C; 1 h;
2: With water; ammonium chloride in diethyl ether
参考文献
Council of Scientific and Industrial Research
Patent: US2007/4645 A1, 2007 ;
Location in patent: Page/Page column 8-9 ;
反应条件
in tetrahydrofuran
T=-78 - 20°C;
参考文献
Joncour, Agnes; Decor, Anne; Liu, Jian-Miao; Tran Huu Dau, Marie-Elise; Baudoin, Olivier
Chemistry - A European Journal, 2007 , vol. 13, # 19 p. 5450 - 5465
反应条件
1: ethyl bromide With iodine; magnesium in diethyl ether
2: piperonal in diethyl ether
T=0 - 20°C; Grignard reaction; Further stages.;
参考文献
Reigada, Juliana B.; Tcacenco, Celize. M.; Andrade, Leandro H.; Kato, Massuo J.; Porto, Andre L.M.; Lago, Joao Henrique G.
Tetrahedron Asymmetry, 2007 , vol. 18, # 9 p. 1054 - 1058
反应条件
lithium aluminium tetrahydride in diethyl ether
0.5 h; Heating;
参考文献
Daukshas, V. K.; Gaidyalis, P. G.; Udrenaite, E. B.; Labanauskas, L. K.; Gasperavichene, G. A.; et al.
Pharmaceutical Chemistry Journal, 1989 , vol. 23, # 12 p. 990 - 995
Khimiko-Farmatsevticheskii Zhurnal, 1989 , vol. 23, # 12 p. 1466 - 1470
反应条件
1: ethyl bromide With magnesium in diethyl ether
2: piperonal in diethyl ether; toluene
T=20°C; 14 h;
参考文献
Sharma, Anuj; Joshi, Bhupendra P.; Singh, Narendra P.; Sinha, Arun K.
Tetrahedron, 2006 , vol. 62, # 5 p. 847 - 851
参考文献
Yoshimitsu, Takehiko; Arano, Yoshimasa; Nagaoka, Hiroto
Journal of the American Chemical Society, 2005 , vol. 127, # 33 p. 11610 - 11611
参考文献
Mameli
Gazzetta Chimica Italiana, 1904 , vol. 34 II, p. 409
Atti della Accademia Nazionale dei Lincei, Classe di Scienze Fisiche, Matematiche e Naturali, Rendiconti, 1904 , vol. <5>13 II, p. 316
