DL-ALPHA-(甲胺基甲基)苄醇合成路线 （共 40 条）
反应条件
(i) nBuLi, hexane, THF, (ii) aq. HCl, (iii) H2, Pd-C, MeOH; Multistep reaction;
参考文献
Peterson,D.J.; Ward,J.F.
Journal of Organometallic Chemistry, 1974 , vol. 66, p. 209 - 217
参考文献
Schlecker,R. et al.
Helvetica Chimica Acta, 1978 , vol. 61, p. 512 - 526
参考文献
Levi
Farmacija SofiaChem.Abstr., 1958 , vol. 8, # 1 p. 31,33
Farmacija SofiaChem.Abstr., 1960 , p. 10934
反应条件
unter Druck.Hydrogenation;
参考文献
Hyde; Browning; Adams
Journal of the American Chemical Society, 1928 , vol. 50, p. 2290
反应条件
Erwaermen des Reaktionsprodukts mit wss. Salzsaeure;
参考文献
Bhatnagar et al.
Journal of the Indian Chemical Society, 1937 , vol. 14, p. 344,345
反应条件
trifluorormethanesulfonic acid
参考文献
Klumpp; Aguirre; Sanchez Jr.; de Leon
Organic letters, 2001 , vol. 3, # 17 p. 2781 - 2784
反应条件
1: 98 percent / Et3N / ethanol / 2 h / Heating
2: 58 percent / pyridine, CrO3 / CH2Cl2 / 0.33 h
3: 39 percent / H2 / Raney nickel / ethanol / 3 h
View Scheme
参考文献
Temple Jr.; Wheeler; Elliott; Rose; Comber; Montgomery
Journal of Medicinal Chemistry, 1983 , vol. 26, # 1 p. 91 - 95
反应条件
in chloroform
0.5 h; Ambient temperature;
参考文献
Moehre, H.; Kamper, Ch.
Pharmazie, 1983 , vol. 38, # 8 p. 512 - 520
反应条件
phosphorous pentoxide in chloroform
1 h; Ambient temperature;
参考文献
Moehre, H.; Kamper, Ch.
Pharmazie, 1983 , vol. 38, # 8 p. 512 - 520
反应条件
1: With chromium(VI) oxide; sulfuric acid
T=40°C; Oxidation; 2 h;
2: With sodium nitrite in dichloromethane
T=20°C; Nitrosation;
参考文献
Saavedra, Joseph E.; Farnsworth, David W.
Organic Preparations and Procedures International, 1991 , vol. 23, # 2 p. 139 - 146
