(R)-(-)-4-烯基-2-戊醇合成路线 （共 30 条）
反应条件
copper(l) iodide in tetrahydrofuran T=-20°C; 12 h;
参考文献
Chowdhury, Partha Sarathi; Gupta, Priti; Kumar, Pradeep
Tetrahedron Letters, 2009 , vol. 50, # 51 p. 7188 - 7190
反应条件
1: in diethyl ether T=-78°C; 1 h; 2: With dihydrogen peroxide; sodium hydroxide in diethyl ether; water T=25°C; 2 h;
参考文献
Shelke, Anil M.; Rawat, Varun; Suryavanshi, Gurunath; Sudalai, Arumugam
Tetrahedron Asymmetry, 2012 , vol. 23, # 22-23 p. 1534 - 1541
参考文献
Targacept, Inc.
Patent: US6492399 B1, 2002 ;
反应条件
copper(l) iodide in tetrahydrofuran T=-40°C; Inert atmosphere;
参考文献
Schmidt, Bernd; Kunz, Oliver
European Journal of Organic Chemistry, 2012 , # 5 p. 1008 - 1018
反应条件
sodium hydroxide in methanol T=0°C; 2 h;
参考文献
Reddy; Yucel; Ramachandran
Journal of Organic Chemistry, 2001 , vol. 66, # 7 p. 2512 - 2514
反应条件
CALB in phosphate buffer T=30°C; pH=7.3; 16 h;
参考文献
Banwell, Martin G; Loong, David T J
Organic and biomolecular chemistry, 2004 , vol. 2, # 14 p. 2050 - 2060
反应条件
1: trans vinyl bromide With magnesium; ethylene dibromide in tetrahydrofuran 0.5 h; 2: (R)-(+)-propylene oxide in tetrahydrofuran T=-40°C; 4 h;
参考文献
Yadav; Kumar, N. Niranjan; Reddy, M. Sridhar; Prasad
Tetrahedron, 2007 , vol. 63, # 12 p. 2689 - 2694
反应条件
ammonia; sodium in tetrahydrofuran T=-78°C; 0.25 h;
参考文献
Angewandte Chemie, , vol. 104, # 10 p. 1366 - 1367
反应条件
Candida antarctica lipase B in phosphate buffer T=25°C; pH=7.6; 16 h;
参考文献
Banwell; Jolliffe; Loong; McRae; Vounatsos
Journal of the Chemical Society. Perkin Transactions 1, 2002 , vol. 2, # 1 p. 22 - 25
反应条件
in diethyl ether 3 h, -78°C; NMR;
参考文献
Burgos, Carlos H.; Canales, Eda; Matos, Karl; Soderquist, John A.
Journal of the American Chemical Society, 2005 , vol. 127, # 22 p. 8044 - 8049
