4-羟甲基哌啶合成路线

161975-39-91-BOC-4-甲磺酰基氧甲基哌啶

参考文献

DONG-A PHARM.CO., LTD.; KIM, Soon-Hoe; IM, Weon-Bin; CHOI, Sung-Hak; CHOI, Sun-Ho; SOHN, Ju-Hee; SUNG, Hyun-Jung; KIM, Mi-Yeon; CHO, Kang-Hun; SOHN, Tae-Kyoung
Patent: WO2011/132901 A2, 2011 ;
WO 2011/132901 A2

6457-49-44-羟甲基哌啶+

541-41-3氯甲酸乙酯

118156-56-24-(羟基甲基)-1-哌啶羧酸乙酯

参考文献

VERTEX PHARMACEUTICALS, INCORPORATED
Patent: WO2006/23852 A2, 2006 ;
Location in patent: Page/Page column 80; 81 ;
WO 2006/023852 A2

118156-56-24-(羟基甲基)-1-哌啶羧酸乙酯

参考文献

Janssen Pharmaceutica N.V.
Patent: US5100893 A1, 1992 ;

6457-49-44-羟甲基哌啶+

98-88-4苯甲酰氯

19980-00-8

参考文献

AXYS PHARMACEUTICALS, INC.
Patent: WO2006/69096 A1, 2006 ;
Location in patent: Page/Page column 96 ;
WO 2006/069096 A1

6457-49-44-羟甲基哌啶+

613-90-1苯甲酰腈

19980-00-8

参考文献

Akula; Kabalka
Journal of Labelled Compounds and Radiopharmaceuticals, 1999 , vol. 42, # SUPPL. 1 p. S782-S784

6457-49-44-羟甲基哌啶

176967-62-7

参考文献

Waterhouse; Collier; O'Brien
Journal of Labelled Compounds and Radiopharmaceuticals, 1996 , vol. 38, # 3 p. 215 - 226

6457-49-44-羟甲基哌啶

120014-29-1

参考文献

Akula; Kabalka
Journal of Labelled Compounds and Radiopharmaceuticals, 1999 , vol. 42, # SUPPL. 1 p. S782-S784

6457-49-44-羟甲基哌啶+

459-57-4对氟苯甲醛

683772-13-6

参考文献

Apodaca, Richard L.; Dvorak, Curt A.; Shah, Chandravadan R.; Xiao, Wei
Patent: US2004/87573 A1, 2004 ;
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US 20040087573 A1

6457-49-44-羟甲基哌啶+

107-31-3甲酸甲酯

835633-50-6N-甲酰基-4-哌啶甲醇

参考文献

AMGEN INC.
Patent: WO2005/9978 A1, 2005 ;
Location in patent: Page 63 ;

6457-49-44-羟甲基哌啶+

181704-15-4

857650-84-1

参考文献

Brudeli, Bjarne; Moltzau, Lise Roman; Andressen, Kjetil Wessel; Krobert, Kurt A.; Klaveness, Jo; Levy, Finn Olav
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 24 p. 8600 - 8613