N-甲氧基-N-甲基己酰胺合成路线 （共 11 条）
反应条件
in tetrahydrofuran T=0°C; 1 h;
参考文献
Zhao, Zhong; Araldi, Gian Luca; Xiao, Yufang; Reddy, Adulla P.; Liao, Yihua; Karra, Srinivasa; Brugger, Nadia; Fischer, David; Palmer, Elizabeth
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 23 p. 6572 - 6575
反应条件
in tetrahydrofuran T=0 - 20°C; 0.5 h; Yield given;
参考文献
Lee, Na Ra; Lee, Jae In
Synthetic Communications, 1999 , vol. 29, # 8 p. 1249 - 1255
反应条件
in tetrahydrofuran T=0 - 20°C; 1 h; Yield given;
参考文献
Lee, Na Ra; Lee, Jae In
Synthetic Communications, 1999 , vol. 29, # 8 p. 1249 - 1255
反应条件
pyridine in dichloromethane
T=20°C; 1 h;
参考文献
Wagh, Sandip J.; Chowdhury, Raghunath; Mukhopadhyay, Sulekha; Ghosh, Sunil K.
Journal of Labelled Compounds and Radiopharmaceuticals, 2013 , vol. 56, # 13 p. 649 - 654
反应条件
1: oxalyl dichloride; [3H]-Caproic acid With N,N-dimethyl-formamide in dichloromethane
T=20°C; 1 h;
2: O,N-dimethyl-hydroxylamine hydrochloride With pyridine in chloroform
T=0 - 20°C; 1 h;
参考文献
Wilson, Zoe E.; Brimble, Margaret A.
Organic and Biomolecular Chemistry, 2010 , vol. 8, # 6 p. 1284 - 1286
反应条件
disodium hydrogenphosphate; sodium amalgam in methanol
T=0°C; desulfonylation; 1.5 h;
参考文献
Satyamurthi; Singh, Jaimala; Aidhen, Indrapal Singh
Synthesis, 2000 , # 3 p. 375 - 382
反应条件
benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine in N,N-dimethyl-formamide
T=20°C; 18 h;
参考文献
Zhao, Zhong; Araldi, Gian Luca; Xiao, Yufang; Reddy, Adulla P.; Liao, Yihua; Karra, Srinivasa; Brugger, Nadia; Fischer, David; Palmer, Elizabeth
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 23 p. 6572 - 6575
反应条件
in tetrahydrofuran
T=0°C; 0.25 h;
参考文献
Lee, Na Ra; Lee, Jae In
Synthetic Communications, 1999 , vol. 29, # 8 p. 1249 - 1255
反应条件
n-butyllithium; diisopropylamine
1.) Et2O, hexane, -78 deg C, 15 min, 2.) -78 deg C, 5 h; Yield given. Multistep reaction;
参考文献
Turner, James A.; Jacks, Wendy S.
Journal of Organic Chemistry, 1989 , vol. 54, # 17 p. 4229 - 4231
反应条件
1: in tetrahydrofuran
T=0°C; 2 h;
2: With hydrogenchloride; water in tetrahydrofuran
参考文献
SOLVAY PHARMACEUTICALS B.V.
Patent: US2007/142362 A1, 2007 ;
Location in patent: Page/Page column 10 ;
US 20070142362 A1
