1-溴-2,2-二甲基丙烷合成路线 （共 70 条）
反应条件
tetra-n-butylammonium tetrafluoroborate in N,N-dimethyl-formamide T=25°C; Rate constant;
参考文献
Daasbjerg, Kim; Lund, Henning
Acta Chemica Scandinavica, 1993 , vol. 47, # 6 p. 597 - 604
反应条件
hydrogen sulfide ion in gas ΔH0Rx; Thermodynamic data;
参考文献
DePuy, Charles H.; Gronert, Scott; Mullin, Amy; Bierbaum, Veronica M.
Journal of the American Chemical Society, 1990 , vol. 112, # 24 p. 8650 - 8655
反应条件
1: NaH / dimethylformamide / 1.) 1 h, 2.) reflux, 8 h 2: AlCl3 / toluene / 1 h / 60 °C View Scheme
参考文献
Bonacchi; Agostini; Di Marco; Borgianni; Ballati; Boni; Castellucci; Evangelista; Toja
Farmaco, 1995 , vol. 50, # 5 p. 333 - 339
反应条件
lithium perchlorate (anodic oxidation);
参考文献
Becker,J.Y.
Journal of Organic Chemistry, 1977 , vol. 42, p. 3997 - 4000
反应条件
hydrogen iodide; tri-n-butylhexadecylphosphonium bromide T=105°C; 60 h;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , # 18 p. 2309 - 2312
反应条件
tetra-n-butylammonium tetrafluoroborate in N,N-dimethyl-formamide T=25°C; Rate constant;
参考文献
Daasbjerg, Kim; Lund, Henning
Acta Chemica Scandinavica, 1993 , vol. 47, # 6 p. 597 - 604
反应条件
1-methyl-pyrrolidin-2-one; triphenylphosphine
参考文献
Zimmerman,A.H. et al.
Journal of the American Chemical Society, 1977 , vol. 99, # 22 p. 7203 - 7209
反应条件
(i) Mg, ether, (ii) /BRN= 605384/, (iii) aq. H2SO4; Multistep reaction;
参考文献
Fujii; Hiraga; Yoshifuji; et al.
Chemical and Pharmaceutical Bulletin, 1978 , vol. 26, # 10 p. 3233 - 3237
反应条件
magnesium; zinc(II) chloride in tetrahydrofuran
参考文献
ELAN PHARMACEUTICALS, INC.; PHARMACIA and UP JOHN COMPANY
Patent: WO2005/95326 A2, 2005 ;
Location in patent: Page/Page column 133 ;
WO 2005/095326 A2
参考文献
Ingold, K. U.; Nonhebel, D. C.; Walton, J. C.
Journal of Physical Chemistry, 1986 , vol. 90, # 13 p. 2859 - 2869
