potassium carbonate; potassium iodide in N,N-dimethyl-formamide
T=110°C; 6 h;
参考文献
He, Huarui; Mortellaro, Mark A.; Leiner, Marc J. P.; Fraatz, Robert J.; Tusa, James K.
Journal of the American Chemical Society, 2003 , vol. 125, # 6 p. 1468 - 1469
1: With sodium sulfite in 1,4-dioxane; water
16 h; Heating / reflux;
2: With thionyl chloride; N,N-dimethyl-formamide in 1,4-dioxane; water
2 h; Heating / reflux;
参考文献
ASTEX THERAPEUTICS LIMITED
Patent: WO2006/77414 A1, 2006 ;
Location in patent: Page/Page column 158-159 ;
WO 2006/077414 A1