N,N-二甲基苯甲酰胺合成路线 （共 319 条）
反应条件
Pd/C; hydrogen
T=160°C; 16 h;
参考文献
Beamson, Graham; Papworth, Adam J.; Philipps, Charles; Smith, Andrew M.; Whyman, Robin
Advanced Synthesis and Catalysis, 2010 , vol. 352, # 5 p. 869 - 883
反应条件
tri-ruthenium(0)dodecacarbonyl; hydrogen; molybdenum hexacarbonate in ethylene glycol dimethyl ether
T=160°C; P=75007.5 Torr; 16 h; Inert atmosphere;
参考文献
Beamson, Graham; Papworth, Adam J.; Philipps, Charles; Smith, Andrew M.; Whyman, Robin
Advanced Synthesis and Catalysis, 2010 , vol. 352, # 5 p. 869 - 883
反应条件
1: 75 percent / LiTMP / tetrahydrofuran / -78 °C
2: 1.) t-BuLi/TMEDA / 1.) THF, -78 deg C
3: 1.) TBAF 2.) Et3BHLi / 1.) THF, RT 2.) THF, reflux
View Scheme
参考文献
Cuevas, J.-C.; Patil, P.; Snieckus, V.
Tetrahedron Letters, 1989 , vol. 30, # 43 p. 5841 - 5844
反应条件
tert.-butyl lithium
1) THF, -78 deg C, 30-90 min, 2) to r.t., 6 h; Yield given. Multistep reaction;
参考文献
Gharpure; Stoller; Bellamy; Firnau; Snieckus
Synthesis, 1991 , # 12 p. 1079 - 1082
反应条件
tert.-butyl lithium
1.) THF, -5 degC, 45 min; 2.) THF, 3 h; Yield given. Multistep reaction;
参考文献
Sundberg, Richard J.; Broome, Rita; Walters, Claudia Powers; Schnur, Dora
Journal of Heterocyclic Chemistry, 1981 , vol. 18, p. 807 - 809
反应条件
2: aqueous H2SO4
View Scheme
参考文献
Gaudemar-Bardone
Annales de Chimie (Cachan, France), 1958 , vol. <13> 3, p. 52,102
反应条件
lithium diisopropyl amide in tetrahydrofuran
T=-78°C;
参考文献
Kobayashi, Kazuhiro; Suzuki, Teruhiko; Matsumoto, Naoki
Heterocycles, 2013 , vol. 87, # 7 p. 1507 - 1517
反应条件
n-butyllithium
1) THF, hexane, -78 deg C, 2) THF, hexane, -78 deg C, 30 min; Yield given. Multistep reaction;
参考文献
Degani, Iacopo; Dughera, Stefano; Fochi, Rita; Serra, Emanuela
Journal of Organic Chemistry, 1996 , vol. 61, # 26 p. 9572 - 9577
反应条件
in tetrahydrofuran
36 h; Heating;
参考文献
Cristau, H. J.; Chiche, L.; Kadoura, J.; Torreilles, E.
Tetrahedron Letters, 1988 , vol. 29, # 32 p. 3931 - 3934
反应条件
1) THF, 0 deg C, 1 h, 2) 0 deg C, 3 h; Yield given. Multistep reaction;
参考文献
Kurata, Hiroyuki; Ekinaka, Tatsuya; Kawase, Takeshi; Oda, Masaji
Tetrahedron Letters, 1993 , vol. 34, # 21 p. 3445 - 3448
