(R)-(-)-2-庚醇合成路线 （共 33 条）
反应条件
polymer supported amide of L-phenylalanine in toluene T=0°C; 36 h; Optical yield = 67 percent ee; enantioselective reaction;
参考文献
Applied Catalysis A: General, , vol. 462-463, p. 23 - 30
反应条件
nitrogen; copper monoiodide in tetrahydrofuran
参考文献
Rhodia ChiRex, Inc.
Patent: US2002/119909 A1, 2002 ;
反应条件
Leifsonia sp. S749 cells alcohol dehydrogenase; β-NADP+; isopropyl alcohol in phosphate buffer T=25°C; pH=7.0; 24 h;
参考文献
Inoue, Kousuke; Makino, Yoshihide; Itoh, Nobuya
Tetrahedron Asymmetry, 2005 , vol. 16, # 15 p. 2539 - 2549
反应条件
(R)-boranyl-(1-phenyl-ethyl)-amine; boron trifluoride in tetrahydrofuran T=0°C; 0.5 h; other asymmetric reagents, stereoselectivity; Product distributionMechanism;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 231 - 235
反应条件
hydrogen; platinum(IV) oxide in ethanol 2 h; Ambient temperature; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 31, # 3 p. 837 - 851
反应条件
complex from (4R,5R)-2,2-dimethyl-α,α,α',α'-tetraphenyl-1,3-dioxolane and tris(isopropoxy)chlorotitane in tetrahydrofuran T=-15°C; Yield given. Yields of byproduct given;
参考文献
Helvetica Chimica Acta, , vol. 70, p. 954 - 974
反应条件
Sulfolobus acidocaldarius DSM 639 in phosphate buffer Title compound not separated from byproducts;
参考文献
Organic and Biomolecular Chemistry, , vol. 3, # 14 p. 2652 - 2656
反应条件
1: mCPBA, KF / CH2Cl2 / 24 h 3: LiAlH4 / diethyl ether / 3 h / Ambient temperature View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 9, # 2 p. 341 - 350
反应条件
2: LiAlH4 / diethyl ether / 3 h / Ambient temperature View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 9, # 2 p. 341 - 350
反应条件
Candida antarctica lipase B immobilized on acrylic resin catalyst in pentane T=20 - 25°C; 24 h; Enzymatic reaction; optical yield given as percent eeenantioselective reaction;
参考文献
Strohalm, Hedwig; Dold, Susanne; Pendzialek, Kathrin; Weiher, Monika; Engel, Karl-Heinz
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 10 p. 6328 - 6333
