(R)-(-)-2-辛醇合成路线 （共 140 条）
反应条件
1: dimethyl zinc With C32H34N4NiO2 in toluene T=0 - 20°C; 0.5 h; Inert atmosphereSchlenk technique; 2: hexanal in toluene T=20°C; 8 h; Schlenk techniqueInert atmosphere; enantioselective reaction;
参考文献
Tetrahedron, , vol. 69, # 2 p. 551 - 558
反应条件
hydrogen; lipase B from Candida antarctica in toluene T=70°C; P=750.075 Torr; 48 h; Resolution of racemateEnzymatic reaction;
参考文献
European Journal of Organic Chemistry, , vol. 2014, # 14 p. 2917 - 2923
反应条件
hydrogen; palladium on activated charcoal in methanol
参考文献
Cainelli, Gianfranco; Manescalchi, Francesco; Martelli, Giorgio; Panunzio, Mauro; Plessi, Laura
Tetrahedron Letters, 1985 , vol. 26, # 28 p. 3369 - 3372
反应条件
1: With hydrogen; [Ru{(S)-MeO-BIPHEP}Br2] in methanol T=25°C; Hydrogenation; P=37503.8 Torr; 2: With nickel desulfurization; Further stages. Title compound not separated from byproducts.;
参考文献
European Journal of Organic Chemistry, , # 8 p. 1535 - 1537
反应条件
1,4-dioxane; water; toluene-4-sulfonic acid in various solvent(s) T=40°C; 5 h;
参考文献
Wallner, Sabine R.; Nestl, Bettina; Faber, Kurt
Tetrahedron, 2005 , vol. 61, # 6 p. 1517 - 1521
反应条件
Candida antarctica lipase B; (η5-C5Ph5)Ru(CO)2Cl; potassium tert-butylate; sodium carbonate in tetrahydrofuran; toluene T=20°C; 20 h;
参考文献
Martin-Matute, Belen; Edin, Michaela; Bogar, Krisztian; Kaynak, F. Betuel; Baeckvall, Jan-E.
Journal of the American Chemical Society, 2005 , vol. 127, # 24 p. 8817 - 8825
反应条件
naphthalene; lithium in tetrahydrofuran; methanol T=20°C; 3.5 h;
参考文献
Behloul, Cherif; Guijarro, David; Yus, Miguel
Tetrahedron, 2005 , vol. 61, # 28 p. 6908 - 6915
反应条件
methanol; potassium carbonate 16 h; RefluxInert atmosphere;
参考文献
Kleman, Patryk; Gonzalez-Liste, Pedro J.; Garcia-Garrido, Sergio E.; Cadierno, Victorio; Pizzano, Antonio
Chemistry - A European Journal, 2013 , vol. 19, # 48 p. 16209 - 16212
反应条件
[(C4Ph4COHOCC4Ph4)(μ-H)][(CO)4Ru2]; Novozym(R) 435; 2,4-dimethylpentan-3-one in toluene T=70°C; P=142.511 Torr; 40 h;
参考文献
Verzijl, Gerard K.M.; De Vries, Johannes G.; Broxterman, Quirinus B.
Tetrahedron Asymmetry, 2005 , vol. 16, # 9 p. 1603 - 1610
反应条件
Arthrobacter atrocyaneus in N,N-dimethyl-formamide T=32°C; 48 h; Microbiological reaction; enantioselective reaction;
参考文献
Silva, Camila R.; Souza, Juliana C.; Araujo, Lidiane S.; Kagohara, Edna; Garcia, Thais P.; Pelizzari, Vivian H.; Andrade, Leandro H.
Journal of Molecular Catalysis B: Enzymatic, 2012 , vol. 83, p. 23 - 28
