2-氧代戊烷-1,5-二甲酸二乙酯合成路线 （共 51 条）
反应条件
hydrogenchloride; formaldehyd in tetrahydrofuran T=20°C;
参考文献
Jin, Young Lee; Hong, Young-Taek; Kim, Sunggak
Angewandte Chemie - International Edition, 2006 , vol. 45, # 37 p. 6182 - 6186
反应条件
acetyl chloride T=20°C; 20 h;
参考文献
Chen, Hong-Bin; Chen, Ling-Yan; Huang, Pei-Qiang; Zhang, Hong-Kui; Zhou, Zhao-Hui; Tsai, Khi-Rui
Tetrahedron, 2007 , vol. 63, # 10 p. 2148 - 2152
反应条件
water; bis-[(trifluoroacetoxy)iodo]benzene in acetonitrile T=0°C; 0.5 h;
参考文献
Barton, Derek H. R.; Jaszberenyi, Joseph Cs.; Shinada, Tetsuro
Tetrahedron Letters, 1993 , vol. 34, # 45 p. 7191 - 7194
反应条件
1: ethanol / 3 h / on the boiling water bath, then stand overnight 2: hydrochloric acid / 0.25 h / boiling water bath View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 22, p. 1275 - 1280
反应条件
1: Et3N / CH2Cl2 / 2 h / 0 °C 2: hexamethylditin / benzene / Irradiation 3: 88 percent / aq. HCHO; HCl / tetrahydrofuran / 20 °C View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 45, # 37 p. 6182 - 6186
反应条件
1: hexamethylditin / benzene / Irradiation 2: 88 percent / aq. HCHO; HCl / tetrahydrofuran / 20 °C View Scheme
参考文献
Angewandte Chemie - International Edition, , vol. 45, # 37 p. 6182 - 6186
反应条件
hexamethyl-distannane in benzene 5 h; UV-irradiation;
参考文献
Lee, Jin Young; Lim, Kyoung-Chan; Meng, Xiangjian; Kim, Sunggak
Synlett, 2010 , # 11 p. 1647 - 1650
反应条件
1: benzene / 48 h / Heating 2: H2 / 5percent palladium on charcoal / ethanol / 16 h / Ambient temperature 3: tert-butyl hypochlorite / diethyl ether / 0.5 h / 0 °C 4: sodium ethoxide / ethanol / 1 h / 40 °C 5: 5percent sulfuric acid / H2O / 2 h / Ambient temperature View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 31, # 3 p. 887 - 894
反应条件
1: H2 / 5percent palladium on charcoal / ethanol / 16 h / Ambient temperature 2: tert-butyl hypochlorite / diethyl ether / 0.5 h / 0 °C 3: sodium ethoxide / ethanol / 1 h / 40 °C 4: 5percent sulfuric acid / H2O / 2 h / Ambient temperature View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 31, # 3 p. 887 - 894
反应条件
1: H2 / PtO2 / ethanol 2: aq. HCl / ethanol View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 17, p. 2424 - 2435
