4-(4-氯苯基)-6-甲基-2-氧代-1,2,3,4-四氢嘧啶-5-羧酸乙酯合成路线 （共 12 条）
反应条件
copper(II) bis(trifluoromethanesulfonate) in ethanol T=100°C; Biginelli reaction; 1 h; Microwave irradiationInert atmosphere;
参考文献
Pasunooti, Kalyan Kumar; Chai, Hua; Jensen, Chantel Nixon; Gorityala, Bala Kishan; Wang, Siming; Liu, Xue-Wei
Tetrahedron Letters, 2011 , vol. 52, # 1 p. 80 - 84
反应条件
1: 4-chloro-1-hydroxymethyl-benzene With Bi(NO3)3 in acetonitrile Heating; 2: ethyl acetoacetate; urea in acetonitrile Heating;
参考文献
Khosropour, Ahmad R.; Khodaei, Mohammd M.; Beygzadch, Mojtaba; Jokar, Mahbubeh
Heterocycles, 2005 , vol. 65, # 4 p. 767 - 773
反应条件
iron(III) tosylate hexahydrate in isopropyl alcohol T=70°C; Biginelli Pyrimidone Synthesis; 21 h;
参考文献
Starcevich, Jacob T.; Laughlin, Thomas J.; Mohan, Ram S.
Tetrahedron Letters, 2013 , vol. 54, # 8 p. 983 - 985
反应条件
ZnO T=60°C; Biginelli Pyrimidone Synthesis; 12 h;
参考文献
Tamaddon, Fatemeh; Moradi, Somayeh
Journal of Molecular Catalysis A: Chemical, 2013 , vol. 370, p. 117 - 122
反应条件
1: 4-chloro-benzyl chloride With Bi(NO3)3; tetrabutyl ammonium fluoride T=120°C; 2: ethyl acetoacetate; urea T=120°C; Biginelli reaction;
参考文献
Khodaei, Mohammad Mehdi; Khosropour, Ahmad Reza; Jowkar, Mahbubeh
Synthesis, 2005 , # 8 art. no. Z21704SS, p. 1301 - 1304
参考文献
Salehi, Peyman; Dabiri, Minoo; Zolfigol, Mohammad Ali; Baghbanzadeh, Mostafa
Heterocycles, 2005 , vol. 65, # 5 p. 1177 - 1181
反应条件
FeCl3*6H2O Biginelli reaction; 0.25 h; Microwave irradiationneat (no solvent);
参考文献
Majd, Mahdieh Mozaffari; Saidi, Kazem; Khabazzadeh, Hojatollah
Phosphorus, Sulfur and Silicon and the Related Elements, 2010 , vol. 185, # 2 p. 325 - 329
反应条件
Bi(NO3)3 T=100°C; Biginelli reaction; 0.416667 h;
参考文献
Khosropour, Ahmad R.; Khodaei, Mohammad M.; Beygzadeh, Mojtaba
Heteroatom Chemistry, 2007 , vol. 18, # 6 p. 684 - 687
反应条件
Bi(NO3)3*ZnCl2*Al2O3 T=140°C; 0.333333 h; microwave irradiation;
参考文献
Journal of Heterocyclic Chemistry, , vol. 45, # 2 p. 349 - 357
反应条件
1: 4-methylene-oxetan-2-one; ethanol; 4-chlorobenzaldehyde With silica sulfuric acid Biginelli-type condensation; 0.0833333 h; Neat (no solvent)Reflux; 2: urea Biginelli-type condensation; Neat (no solvent)Reflux;
参考文献
Rostamnia, Sadegh; Lamei, Kamran
Chinese Chemical Letters, 2012 , vol. 23, # 8 p. 930 - 932
