叶酸合成路线 - 魔法化学

58-05-9亚叶酸+10016-20-3α-环糊精→59-30-3叶酸

参考文献

EP427078 A1, ;

188497-71-4→59-30-3叶酸

参考文献

US4931442 A1, ;

65165-92-6DL-叶酸+497-15-4羟基丙二醛+4271-30-1N-(4-氨基苯甲酰)-L-谷氨酸→59-30-3叶酸

参考文献

US5410056 A1, ;

59-30-3叶酸→31690-09-2L-5-甲基四氢叶酸

参考文献

WATSON LABORATORIES, INC.; BHANU, Manjunath, Narayan; SINHA, Chandrasekhar; AHER, Bhupesh; SONAR, Jitendra
Patent: WO2013/25203 A1, 2013 ;

59-30-3叶酸→4230-33-5N-(4-氨基苯甲酰基)-DL-谷氨酸+712-30-12-氨基-4-羟基蝶啶-6-甲醛

参考文献

Thomas, Andres H.; Suarez, Gustavo; Cabrerizo, Franco M.; Garcia Einschlag, Fernando S.; Martino, Raul; Baiocchi, Claudio; Pramauro, Edmondo; Capparelli, Alberto L.
Helvetica Chimica Acta, 2002 , vol. 85, # 8 p. 2300 - 2315

59-30-3叶酸→54-62-6氨基蝶呤

参考文献

Zebala, John A.
Patent: US7235660 B1, 2007 ;
Location in patent: Page/Page column 2-3 ;

59-30-3叶酸→37793-53-6N10-(三氟乙酰基)蝶酸

参考文献

Luo, Jin; Smith, Michael D.; Lantrip, Douglas A.; Wang, Susan; Fuchs
Journal of the American Chemical Society, 1997 , vol. 119, # 42 p. 10004 - 10013

59-30-3叶酸→4271-30-1N-(4-氨基苯甲酰)-L-谷氨酸+948-60-7蝶呤-6-羧酸+712-30-12-氨基-4-羟基蝶啶-6-甲醛

参考文献

Vorobey, Pavel; Steindal, Arnfinn Engeset; Off, Morten Kristian; Vorobey, Alexander; Moan, Johan
Photochemistry and Photobiology, 2006 , vol. 82, # 3 p. 817 - 822

59-30-3叶酸→712-30-12-氨基-4-羟基蝶啶-6-甲醛+4271-30-1N-(4-氨基苯甲酰)-L-谷氨酸

参考文献

Cabrerizo, Franco M.; Laura Dantola; Petroselli, Gabriela; Capparelli, Alberto L.; Thomas, Andres H.; Braun, Andre M.; Lorente, Carolina; Oliveros, Esther
Photochemistry and Photobiology, 2007 , vol. 83, # 3 p. 526 - 534

59-30-3叶酸→4271-30-1N-(4-氨基苯甲酰)-L-谷氨酸+150-13-0对氨基苯甲酸+948-60-7蝶呤-6-羧酸+712-30-12-氨基-4-羟基蝶啶-6-甲醛

参考文献

Patro, Birija S.; Adhikari, Soumyakanti; Mukherjee, Tulsi; Chattopadhyay, Subrata
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 1 p. 67 - 71