2-(4-氯丙氧基)-2-甲基丙酰氯合成路线 (共 23 条)
反应条件
thionyl chloride; chloroform
参考文献
Bulletin de la Societe Chimique de France, , p. 776,780, 781
反应条件
1: NaOH / ethanol / 24 h / Heating 2: SOCl2 / 1 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 37, # 11 p. 1712 - 1719
反应条件
1: ethanol / anschliessend Erwaermen mit wss. Natronlauge 2: chloroform; thionyl chloride View Scheme
参考文献
Bulletin de la Societe Chimique de France, , p. 776,780, 781
反应条件
in xylene 2 h; Heating;
参考文献
Metz; Specker
Arzneimittel-Forschung/Drug Research, 1980 , vol. 30, # 116 p. 2014 - 2019
反应条件
in pyridine; Petroleum ether 3 h; Heating;
参考文献
Ribalta; Artus; Salvador; Roma; Vilageliu; Freixes; Bruseghini
Arzneimittel-Forschung/Drug Research, 1981 , vol. 31, # 10 A p. 1782 - 1786
反应条件
4-(N,N-dimethlyamino)pyridine in tetrahydrofuran T=75°C; 2 h;
参考文献
Jang, Doo Ok; Cho, Dae Hyan; Kim, Joong-Gon
Synthetic Communications, 2003 , vol. 33, # 16 p. 2885 - 2890
反应条件
pyridine; ethanol; benzene
参考文献
Julia
Bulletin de la Societe Chimique de France, 1956 , p. 776,780, 781
反应条件
1: 83 percent / NH3 / diethyl ether / -40 °C 2: nitric acid, acetic anhydide, trifluoroacetic anhydride, / CDCl3 / -60 °C 3: 98 percent / sodium hydride / dimethylformamide View Scheme
参考文献
Clewley, Robin G.; Fischer, Alfred; Henderson, George N.
Canadian Journal of Chemistry, 1989 , vol. 67, p. 1472 - 1479
反应条件
(i), (ii) /BRN= 2212044/; Multistep reaction;
参考文献
Metz; Specker
Arzneimittel-Forschung/Drug Research, 1977 , vol. 27, # 7 p. 1421 - 1424