N-Ts-甘氨酸乙酯合成路线

1629-58-91-戊烯-3-酮+5465-67-8N-Ts-甘氨酸乙酯→3284-52-43-羟基-3-甲基-1-对甲苯磺酰基吡咯烷-2-甲酸乙酯

参考文献

SEPRACOR INC.
Patent: US2005/143443 A1, 2005 ;
Location in patent: Page/Page column 39-40 ;

3299-38-51-二乙基氨-3-丁酮+5465-67-8N-Ts-甘氨酸乙酯→3284-52-43-羟基-3-甲基-1-对甲苯磺酰基吡咯烷-2-甲酸乙酯

参考文献

PRESIDENT AND FELLOWS OF HARVARD COLLEGE; THE BRIGHAM AND WOMEN'S HOSPITAL, INC.; TRUSTEES OF BOSTON UNIVERSITY
Patent: WO2009/23272 A1, 2009 ;
Location in patent: Page/Page column 36 ;

5465-67-8N-Ts-甘氨酸乙酯+78-94-4丁烯酮→3284-52-43-羟基-3-甲基-1-对甲苯磺酰基吡咯烷-2-甲酸乙酯

参考文献

Makino, Kazuishi; Suzuki, Tatsuya; Hamada, Yasumasa
Bulletin of the Chemical Society of Japan, 2004 , vol. 77, # 9 p. 1649 - 1653

623-33-6甘氨酸乙酯盐酸盐+98-59-9对甲苯磺酰氯→5465-67-8N-Ts-甘氨酸乙酯

参考文献

SEPRACOR INC.
Patent: US2005/143443 A1, 2005 ;
Location in patent: Page/Page column 6; 39-40 ;

83670-53-5→5465-67-8N-Ts-甘氨酸乙酯

参考文献

Shimizu, Makoto; Sahara, Tetsuya; Hayakawa, Ryuuichirou
Chemistry Letters, 2001 , # 8 p. 792 - 793

64-17-5乙醇+1080-44-0N-对甲苯磺酰甘氨酸→5465-67-8N-Ts-甘氨酸乙酯

参考文献

DeRuiter; Brubaker; Garner; Barksdale; Mayfield
Journal of Pharmaceutical Sciences, 1987 , vol. 76, # 2 p. 149 - 152

941-55-9对甲苯磺酰叠氮+18295-66-4→5465-67-8N-Ts-甘氨酸乙酯

参考文献

Xu, Yong; Zhu, Shizheng
Tetrahedron, 2001 , vol. 57, # 18 p. 3909 - 3913

98-59-9对甲苯磺酰氯+459-73-42-胺基乙酸乙酯→5465-67-8N-Ts-甘氨酸乙酯

参考文献

Pham, Cindy C.; Park, Michelle H.; Pham, Jenny Y.; Martin, Sadie G.; Schramm, Michael P.
Synthesis (Germany), 2013 , vol. 45, # 9 art. no. SS-2012-M1003-OP, p. 1165 - 1173

1666-17-7苯甲醛对甲苯磺酰腙+105-36-2溴乙酸乙酯→5465-67-8N-Ts-甘氨酸乙酯+100-47-0苯甲腈

参考文献

Tang, Hai-Tao; Zhou, Yun-Bing; Zhu, Yu; Sun, Hong-Chao; Lin, Min; Zhan, Zhuang-Ping
Chemistry - An Asian Journal, 2014 , vol. 9, # 5 p. 1278 - 1281

1576-35-8对甲苯磺酰肼→5465-67-8N-Ts-甘氨酸乙酯

参考文献

Tang, Hai-Tao; Zhou, Yun-Bing; Zhu, Yu; Sun, Hong-Chao; Lin, Min; Zhan, Zhuang-Ping
Chemistry - An Asian Journal, 2014 , vol. 9, # 5 p. 1278 - 1281