(Z)-3-氨基-3-苯基-2-丙烯酸乙酯合成路线 （共 15 条）
反应条件
pyridine; thionyl chloride 1.) CH2Cl2, from 0 deg C to 20 deg C, 1 h, 2.) CH2Cl2, 20 deg C, 18 h; Multistep reaction;
参考文献
Eynde, Jean-Jacques Vanden; Mayence, Annie; Maquestiau, Andre; Anders, Ernst
Heterocycles, 1994 , vol. 37, # 2 p. 815 - 822
反应条件
hydroxylamine hydrochloride in dichloromethane 20 h; Heating;
参考文献
Valduga, Claudete J.; Santis, Denise B.; Braibante, Hugo S.; Braibante, Mara E. F.
Journal of Heterocyclic Chemistry, 1999 , vol. 36, # 2 p. 505 - 508
反应条件
oxygen; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione in dimethyl sulfoxide T=70°C; 3 h; TemperatureTime;
参考文献
Gade, Narendar Reddy; Devendram; Pal, Manojit; Iqbal, Javed
Chemical Communications, 2013 , vol. 49, # 72 p. 7926 - 7928
反应条件
ammonium acetate; ethyl orthosilicate in ethanol
Heating;
参考文献
Zhao, Yuanhong; Zhao, Jingfeng; Zhou, Yongyun; Lei, Ze; Li, Liang; Zhang, Hongbin
New Journal of Chemistry, 2005 , vol. 29, # 6 p. 769 - 772
反应条件
zinc oxide; zinc in tetrahydrofuran
2 h; Irradiationsonochemical reaction;
参考文献
Lee, Adam Shih-Yuan; Cheng, Rae-Yi; Pan, Ohm-Guo
Tetrahedron Letters, 1997 , vol. 38, # 3 p. 443 - 446
反应条件
N-ethyl-N,N-diisopropylamine; zinc(II) chloride in 1,2-dichloro-ethane
Blaise reaction; 18 h; Heating;
参考文献
Jae, Hoon Lee; Bo, Seung Choi; Jay, Hyok Chang; Hee, Bong Lee; Yoon, Joo-Yong; Lee, Jaeick; Shin, Hyunik
Journal of Organic Chemistry, 2007 , vol. 72, # 26 p. 10261 - 10263
反应条件
hydrogen; boric acid; nickel in methanol; water; ethyl acetate
24 h;
参考文献
Litinas, Konstantinos E.; Nicolaides, Demetrios N.; Varella, Evangelia A.
Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 3 p. 769 - 774
反应条件
hydrogenchloride; magnesium
参考文献
Monsanto Company
Patent: US4144047 A1, 1979 ;
反应条件
1: 46 percent / triethylamine / CH2Cl2 / 1) 0 deg C, 10min 2) r.t., 24h
2: 66 percent / H2, B(OH)3 / Raney-Ni / methanol; H2O; ethyl acetate / 24 h
View Scheme
参考文献
Litinas, Konstantinos E.; Nicolaides, Demetrios N.; Varella, Evangelia A.
Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 3 p. 769 - 774
反应条件
in diethyl ether
1.) -78 to 0 deg C, 2.) 0 deg C, 1.5 h;
参考文献
Hiyama, Tamejiro; Kobayashi, Kazuhiro; Nishide, Kiyoharu
Bulletin of the Chemical Society of Japan, 1987 , vol. 60, p. 2127 - 2138
