5-苯基-1,3-环己二酮合成路线 （共 57 条）
反应条件
(i) NaOMe, MeOH, (ii) aq. NaOH, (iii) aq. HCl; Multistep reaction;
参考文献
Han, Guang-Fan; Cui, Bin; Chen, Li-Zhuang; Wang, Rui-Hua; Jin, Yan
Journal of Heterocyclic Chemistry, 2011 , vol. 48, # 2 p. 312 - 316
Title/Abstract Full Text View citing articles Show Details
Han, Guang-Fan; Cui, Bin; Chen, Li-Zhuang; Hu, Xiao-Lei
Journal of Heterocyclic Chemistry, 2012 , vol. 49, # 1 p. 195 - 199
反应条件
sodium ethanolate in ethanol
参考文献
Tada, Masahiro; Takakuwa, Takako; Nagai, Masashi; Yoshii, Takao
Agricultural and Biological Chemistry, 1990 , vol. 54, # 11 p. 3061 - 3063
反应条件
sodium hydride T=-10 - 20°C; Michael-Claisen cyclization; 1.66667 h; Inert atmosphereneat (no solvent); regioselective reaction;
参考文献
Sharma, Dharminder; Shil, Arun K.; Singh, Bikram; Das, Pralay
Synlett, 2012 , vol. 23, # 8 p. 1199 - 1204
反应条件
1: EtONa / ethanol / 6 h / Heating 2: 2 N NaOH / 2 h / Heating 3: 5 N H2SO4 / 4.5 h / Heating View Scheme
参考文献
Kesten, Stephen J.; Degnan, Margaret J.; Hung, Jocelyn; McNamara, Dennis J.; Ortwine, Daniel F.; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 19 p. 3429 - 3447
反应条件
barium dihydroxide in methanol Heating;
参考文献
Muxfeldt,H. et al.
Chemische Berichte, 1963 , vol. 96, p. 2943 - 2949
反应条件
1: (i) NaOMe, MeOH, (ii) /BRN= 1967301/, Et2O 2: aq. Ba(OH)2 / methanol / Heating View Scheme
参考文献
Muxfeldt,H. et al.
Chemische Berichte, 1963 , vol. 96, p. 2943 - 2949
反应条件
1: sodium hydroxide 2: sodium ethanolate / Heating View Scheme
参考文献
Cui, Bin; Chen, Li-Zhuang; Hu, Xiao-Lei; Wang, Ming; Han, Guang-Fan
Journal of Heterocyclic Chemistry, 2012 , vol. 49, # 4 p. 900 - 904
反应条件
hydrogen fluoride; SbF5 20 h; Ambient temperature;
参考文献
Repinskaya, I. B.; Barkhutova, D. D.; Makarova, Z. S.; Alekseeva, A. V.; Koptyug, V. A.
Journal of Organic Chemistry USSR (English Translation), 1985 , vol. 21, p. 759 - 767
Zhurnal Organicheskoi Khimii, 1985 , vol. 21, # 4 p. 836 - 845
反应条件
diethyl ether; sodium ethanolate
参考文献
Vorlaender; Knoetzsch
Justus Liebigs Annalen der Chemie, 1897 , vol. 294, p. 332
反应条件
toluene-4-sulfonic acid
参考文献
Piskov,V.B.; Osanova,L.K.
Journal of Organic Chemistry USSR (English Translation), 1967 , vol. 3, p. 1590 - 1592
Zhurnal Organicheskoi Khimii, 1967 , vol. 3, # 9 p. 1633 - 1635
