反应条件
1: 1.) n-BuLi / 1.) THF, hexane, -78 deg C, 1 h, 2.) THF, hexane, a) -20 deg C, 3 h, b) from -78 deg C to RT, 1 h 2: 1.) CuI / 1.) ether, 2.) ether, a) 0 deg C, 2 h, b) RT, 12 h 3: 91 percent / DDQ, H2O / CH2Cl2 / 2 h / Ambient temperature 4: 1.) (COCl)2, DMSO, 2.) Et3N / 1.) CH2Cl2, from -78 deg C to RT, 2 h, 2.) CH2Cl2 View Scheme
参考文献
Tetrahedron, , vol. 52, # 10 p. 3631 - 3658
