dicyclohexyl-carbodiimide in tetrahydrofuran T=5°C; 144 h;

in DCM T=20°C;

pyridine in dichloromethane Cooling with ice;

1: bromoacetic acid N-hydroxysuccinimide ester; triphenylphosphino resin in toluene 16 h; 2: With triethylamine in dichloromethane 16 h; 3: o-hydroxyacetophenone in 1,4-dioxane T=180°C; 0.25 h; microwave irradiation; Further stages.;

1: bromoacetic acid N-hydroxysuccinimide ester; triphenylphosphino resin in toluene 16 h; 2: With triethylamine in dichloromethane 16 h; 3: 2-amino-benzoic acid methyl ester in 1,4-dioxane T=180°C; 0.25 h; microwave irradiation; Further stages.;

1: bromoacetic acid N-hydroxysuccinimide ester; triphenylphosphino resin in toluene 16 h; 2: With triethylamine in dichloromethane 16 h; 3: 2-hydroxy-5-bromo-benzoic aldehyde in 1,4-dioxane T=180°C; 0.25 h; microwave irradiation; Further stages.;

1: bromoacetic acid N-hydroxysuccinimide ester; triphenylphosphino resin in toluene 16 h; 2: With triethylamine in dichloromethane 16 h; 3: 1-amino-4-chlorobenzene-2-carboxylic acid methyl ester in 1,4-dioxane T=180°C; 0.25 h; microwave irradiation; Further stages.;

1: bromoacetic acid N-hydroxysuccinimide ester; triphenylphosphino resin in toluene 16 h; 2: With triethylamine in dichloromethane 16 h; 3: 3-phenyl-1-(2-hydroxyphenyl)-prop-2-ene-1-one in 1,4-dioxane T=180°C; 0.25 h; microwave irradiation; Further stages.;