3-(4-氯苯基)-2-丙炔-1-醇合成路线 (共 9 条)
反应条件
copper(l) iodide; triethylamine; (Ph3P)2Pd(Ph)(I) in chloroform T=40°C; 0.666667 h;
参考文献
Cai, Ming-Zhong; Song, Cai-Sheng; Huang, Xian
Synthetic Communications, 1997 , vol. 27, # 11 p. 1935 - 1942
反应条件
diisobutylaluminium hydride in diethyl ether; hexane T=-78 - 20°C;
参考文献
Nieland, Nick P.R.; Rennison, David; Broadbear, Jillian H.; Purington, Lauren; Woods, James H.; Traynor, John R.; Lewis, John W.; Husbands, Stephen M.
Journal of Medicinal Chemistry, 2009 , vol. 52, # 21 p. 6926 - 6930
反应条件
[5-Cl-2-{(4-Cl-phenyl)-[(E)-HO-imino]methyl}phenyl-PdCl]2 in 1-methyl-pyrrolidin-2-one T=110°C; Sonogashira coupling; 1 h;
参考文献
Advanced Synthesis and Catalysis, , vol. 345, # 9-10 p. 1146 - 1158
反应条件
tetra-n-butylammonium acetate; oxime pladacycles derived from 4,4'-chlorobenzophenone in 1-methyl-pyrrolidin-2-one T=110°C; Sonogashira coupling reaction; 1 h;
参考文献
Alonso, Diego A; Najera, Carmen; Pacheco, M Carmen
Tetrahedron Letters, 2002 , vol. 43, # 51 p. 9365 - 9368
反应条件
dichloro bis(triphenylphosphine)palladium (II)
反应条件
copper(l) iodide; triethylamine; triphenylphosphine T=90°C; Sonogashira coupling; 72 h; Inert atmosphere;
参考文献
Lin, Bo-Nan; Huang, Shao-Hsien; Wu, Wei-Yi; Mou, Chung-Yuan; Tsai, Fu-Yu
Molecules, 2010 , vol. 15, # 12 p. 9157 - 9173
反应条件
(i) Mg, (ii) /BRN= 1209228/; Multistep reaction;
参考文献
Chemische Berichte, , vol. 97, p. 2118 - 2124
反应条件
manganese(IV) oxide; potassium hydroxide in benzene 0.333333 h; Ambient temperature;
参考文献
Bumagin, N. A.; Ponomarev, A. B.; Beletskaya, I. P.
Doklady Chemistry, 1985 , vol. 283, p. 212 - 214
Dokl. Akad. Nauk SSSR Ser. Khim., 1985 , vol. 283, # 3 p. 630 - 633
参考文献
Song, Bo; Li, Lian-Hua; Song, Xian-Rong; Qiu, Yi-Feng; Zhong, Mei-Jin; Zhou, Ping-Xin; Liang, Yong-Min
Chemistry - A European Journal, 2014 , vol. 20, # 20 p. 5910 - 5913